Smooth, ovoid protuberance and “sentinel fold” on barium esophagram in patient with history of acid reflux disease
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Uncommonly, may have irregular border or lobulation
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Represents bulbous tip of prominent gastric fold extending from gastric cardia into distal esophagus
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Located at or above gastroesophageal (GE) junction
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Endoscopic ultrasound
Round, hypoechoic lesion within 2nd and 3rd layers of esophageal wall
Homogeneous echogenicity, richly vascularized
TOP DIFFERENTIAL DIAGNOSES
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Esophageal intramural benign tumors
Hypoechoic with heterogeneous echogenicity on endoscopic US
Arising from muscularis propria layer
Usually have obtuse margin with esophageal wall on esophagram
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Thrombosed esophageal varix
History of portal hypertension and associated findings (cirrhosis, ascites, etc.)
Usually have history of iatrogenic sclerosis (by injecting varices)