7 Pathology of the Nasal Cavity and Paranasal Sinuses
Nonmalignant Pathology of the (Para)nasal Sinuses
Maxillary Sinusitis
Differential Diagnosis
• All causes of obstruction of the maxillary sinus that might induce fluid levels or persistent sinusitis.
• Periapical pathology with inflammation and osteolysis.
• Solitary (fungal) infection.
• Trauma leading to bony dislocation and obstruction of drainage from the sinus.
• Benign and malignant lesions.
Points of Evaluation
• The Waters and Caldwell views are complementary and must always be available for comprehensive evaluation and avoiding misinterpretation due to superimposition of bony structures.
• The area of the natural ostium of the sinus might be obstructed. Computed tomography (CT) can show this obstruction in more detail.
• Pay close attention to unilateral opacities, which are suggestive of tumor or odontogenic infection.
• Complete opacification may be demonstrated after previous endonasal sinus surgery, Caldwell–Luc procedures, or after orbital decompressions in Graves disease. In these patients, conventional radiography is not very useful and CT should be used for a comprehensive detailed examination.
Fig. 7.1 a,b Conventional radiographic views for sinus evaluation.
Adenoid Hypertrophy
Fig. 7.2 Plain radiograph for adenoid evaluation.
Fracture of the Nasal Bone and Retention Cysts
Differential Diagnosis
The radiologic features as seen in Fig. 7.3 are typically pathognomic of retention cysts. In general, these retention cysts must be considered nonpathologic findings. Clinically, they are often asymptomatic or found in patients with minor complaints. In conventional radiographic views, and also on CT, these cysts may be confused with mucosal thickening of the maxillary sinus wall.
Points of Evaluation
In cases of large cysts resulting in obstruction of the maxillary sinus and those accompanied by signs of sinusitis, surgical removal (marsupialization) might be considered to improve drainage.
Fig. 7.3 a–c Mild trauma to the nose. Hematoma made palpation difficult to exclude a fracture.
Fig. 7.3b patient after facial trauma.
Fig. 7.3 c Retention cysts.
Differential Diagnosis
• All etiologies causing mucosal swelling and polyps.
• Chronic rhinosinusitis with or without polyps, associated with hyperreactivity, allergy, smoking.
• Less frequently: Wegener granulomatosis, which typically is associated with destruction of the nasal septum; sinonasal malignancies, which usually show infiltration of surrounding structures and/or bone destruction; and allergic fungal sinusitis.
Points of Evaluation
• Bilateral soft-tissue disease is a reassuring finding, as it usually indicates benign disease such as chronic sinusitis or polyposis.
• Anatomic structures obstructing the sinuses, due to a growth spurt in adolescence, may play a role.
• In cases with symptoms that arise later in life, concomitant secondary pathology is responsible.
• Bone destruction is the hallmark of infiltrating processes and malignant behavior.
Fig. 7.4 a, b Patient with nasal obstruction, smell disorder, and rhinorrhea.
Differential Diagnosis
Nasal polyps, antrochoanal polyps, inverted papilloma, unilateral chronic odontogenic sinusitis with secondary polyps due to chronic infection, unilateral fungal sinusitis, mucoceles, malignancy and cystic fibrosis (similar appearance but commonly bilateral).
Points of Evaluation
• Destruction of bony outlines (with infiltrative characteristics) is suggestive of inverted papilloma, malignancies, or fungal infection.
• Calcifications in the opacified area are suggestive of fungal infection. Resorption of bone around tooth roots suggests odontogenic infection.
• Beware of pathology in the sphenoethmoidal fossa (i.e., juvenile angiofibroma).
Fig. 7.5 Patient with blocked left nose.
Differential Diagnosis
• Conditions causing mucosal swelling and polyps, obstructing the frontal recess.
• Unilateral processes such as inverted papilloma or malignancies.
• Fungal infections.
Points of Evaluation
• The anatomy and pathology of the frontal recess required special attention.
• In cases of persisting drainage problems in the region of the frontal recess, the septum between the frontal sinuses may be removed for establishing drainage by way of the left frontal recess.
• Bony destruction with infiltrative characteristics is suggestive of malignancy.
• Calcifications in the opacified area are suggestive of fungal infections.
Fig. 7.6 a–c Patient with frontal headaches in the region of the right frontal sinus, with extensive pneumatization of both frontal sinuses.
Differential Diagnosis
Nasal polyps, inverted papilloma, unilateral chronic odontogenic sinusitis with secondary polyps, unilateral fungal sinusitis, malignancy cystic fibrosis (commonly bilateral), foreign bodies (e.g. dental filling).
Points of Evaluation
• Destruction of bony outlines with infiltrative characteristics is suggestive of inverted papilloma, malignancies, or fungal infections.
• Calcifications in the opacified area are suggestive of fungal infections.
• History of frequent dental consultations and resorption of bone around tooth roots may indicate odontogenic infections.
• Long-term antibiotics are an essential part of postoperative treatment.
Fig. 7.7 a–c Patient with unilateral pain and pressure in the right maxillary region.
Differential Diagnosis
• All other causes of mucosal swelling and polyps, such as allergy.
• Less frequently: Wegener granulomatosis, which usually shows destruction of the nasal septum; and inverted papilloma or malignancy, often with infiltration of the surrounding bone and/or soft tissues, but rarely bilateral.
Points of Evaluation
• Destruction of bony outlines with infiltrative signs is more characteristic of malignancy.
• Expansion is more likely to be due to benign processes, such as polyposis or mucocele.
• Calcifications in the opacified area are suggestive of fungal infections.
• Resorption of bone around tooth roots indicates dental pulp infections.
• In children, expansion due to polyps can result in cosmetic problems of the exterior aspect of the nose.
Fig. 7.8 a–c Adult patient with known cystic fibrosis and frontal pressure feeling.
Fig. 7.8b Patient with cystic fibrosis history of multiple endonasal surgical procedures.
Fig. 7.8 c CT of a 12-year-old child with cystic fibrosis.
Differential Diagnosis
All underlying causes of mucosal swelling and polyps, such as hyperreactivity, allergy, smoking. Rule out iatrogenic disorders due to extensive previous surgery. Post-traumatic lesions. Pott puffy tumor. Fistulization to the dura (cerebrospinal fluid leakage).
Points of Evaluation
• Sinusitis of the maxillary sinus, which is unresponsive to antibiotics or persists after long-term antibiotics, may be due to fungal infection. Usually, fungal infections affect the maxillary sinus. Less frequently, the frontal sinus is affected.
• Immunosuppressed patients (those with diabetes, human immunodeficiency virus [HIV] infection, or leukemia, and those taking immunosuppressive medication) are at increased risk of fungal infections.
• Opacification with general or focally increased density is suggestive of fungal infection.
• Diffuse infiltration of surrounding structures is seen in some invasive fungal infections (see also “Invasive Fungal Sinusitis,” p.240).
Fig. 7.9 a–c Patient with constant left frontal sinus pressure. CT, coronal (a), sagittal (b), and axial (c).