Anatomic variants
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Accessory spleen: very common. Typically near spleen. Can be intrapancreatic. Can be mistaken for a mass. Should look like spleen on all imaging sequences.
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Duplicated renal collecting system: prone to obstruct/reflux. Has surgical implications.
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Prominent column of Bertin: mimics focal renal mass. Has similar echogenicity, density, and magnetic resonance imaging (MRI) signal intensity to normal renal cortex.
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Pancreas divisum: no ventral/dorsal pancreatic fusion. Predisposes to pancreatitis.
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Pancreatic cleft: fat between normal pancreatic lobulations mimics a mass.
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Chilaiditi sign: colonic hepatic flexure interposed between the liver and the ventral abdominal wall can mimic intraperitoneal free air on radiograph.
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Inferior vena cava (IVC) pseudolipoma: retroperitoneal fat protrudes into the IVC near the cavoatrial junction mimicking a lipoma or thrombus ( Fig. 39.1 ).
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Variant hepatic arterial anatomy: includes accessory (extra) and replaced (arising from the wrong place) arterial anatomy. Crucial for liver and pancreas surgical planning.
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Duplicated IVC: common iliac veins do not join. Left common iliac vein commonly drains to the left renal vein. Affects optimal IVC filter placement.
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Prominent diaphragmatic slip: mimics a focal mass along the liver surface.
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Pseudolipoma of Glisson’s capsule: a piece of colonic epiploic fat located ectopically along the liver capsule.
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Diaphragmatic crus versus retroperitoneal lymphadenopathy: view multiple contiguous axial slices or orthogonal planes (coronal/sagittal) to distinguish.
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Limbus vertebra: well corticated triangular osseous fragment at the anterosuperior corner of a lumbar vertebra resulting from intravertebral herniation of the nucleus pulposus. Mimics a fracture fragment, which would not be well corticated.
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Cisterna chyli: normal fluid-filled tubular lymphatic structure in the right retrocrural space. No arterial or portal venous phase enhancement. Mimics a mass or lymph node.
Techniques and modality-specific pitfalls
Radiography
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Misplaced nasogastric tube: beware of the misplaced tube that is at the margin or beyond the field of view. If one tube is in place, consider that a second tube may be misplaced.
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Intraperitoneal free air can be challenging to detect on supine radiograph. Rigler sign, air on both sides of the bowel wall, can be helpful; however, dilated air-filled loops of bowel closely opposed to each other can mimic this appearance.
Ultrasonography
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Ultrasound settings: adjustment of numerous settings (gain, focal zone, depth, time gain compensation…) can have dramatic effects on image quality, which can mask lesions or create pseudolesions ( Fig. 39.2 ).
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Mirror artifact: a strong reflector (i.e., the diaphragm) creates a false duplicate image of an abdominal structure in the lung. An echogenic liver lesion may be seen in the liver and the lung. Correctly identify the artifact to avoid misdiagnosing a lung mass.
Computed tomography
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Enhancement versus intrinsically hyperdense: cannot distinguish hyperdense renal cyst from enhancing renal mass or hyperdense ingested enteric material from contrast extravasation. If available, a precontrast series is helpful (similar problem affects MRI).
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Liver metastases with background steatosis: low intrinsic background liver attenuation reduces conspicuity or totally obscures liver metastases. In severe hepatic steatosis, metastases appear hyperenhancing to background low attenuation liver.
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Osseous metastasis pseudoprogression: enlarging sclerotic lesions are common after chemotherapy. Reflects treated metastases or progression. Imaging cannot distinguish.
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Vascular mixing artifacts mimicking thrombosis.
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Portal vein: on early postcontrast images, contrast opacified splenic venous blood can mix with nonopacified blood from the superior mesenteric vein.
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IVC: on early postcontrast images, contrast opacified renal vein blood can mix with nonopacified infrarenal IVC blood.
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Bladder is filled with contrast on a noncontrast computed tomography (CT): consider excreted iodinated contrast from prior CT (perhaps at a different institution), excreted iodinated contrast from nonradiology procedure (coronary angiography), or excreted gadolinium from prior MRI. The excreted contrast can mimic renal stones ( Fig. 39.3 ).