Management of Postcatheterization Pseudoaneurysm

22 Management of Postcatheterization Pseudoaneurysm


Wael E.A. Saad and Christine O. Menias

Classification


Arterial pseudoaneurysms are the most common complication (61%) of femoral artery catheterization and are associated with increased morbidity. The overall incidence of postcatheterization pseudoaneurysms ranges from 0.11 to 1.52%. The incidence of access of pseudoaneurysms increases with transcatheter therapeutic interventions (3.5–5.5%) compared with studies confined to diagnostic arterial catheterizations (0.1–1.1%). Due to the ongoing paradigm shift in transcatheter endoluminal interventions as opposed to traditional open surgical interventions, the incidence of postcatheterization pseudoaneurysms is on the rise with ~15,000 femoral pseudoaneurysms diagnosed in the United States annually as of the year 2000.


Numerous methods, with variants within each method, for the management of postcatheterization pseudoaneurysms have been described. For the purposes of this chapter, the two most commonly described approaches (pseudoaneurysm compression and direct percutaneous thrombin injection) and their variant techniques will be discussed.


Indications


Due to the high success rate and low complication rate (see below) with the risk–benefit ratio largely in favor of treatment, the indication for treatment of postcatheterization access pseudoaneurysms is broad and involves almost all patients. However, it is particularly indicated if the postcatheterization access pseudoaneurysms are



  • Painful
  • Affecting ambulation
  • Growing
  • Larger than 1.8–2.0 cm in diameter (>6 cm in volume)

The following are lists that describe the ideal features that make each patient/pseudoaneurysm ideal for either ultrasound-guided compression therapy or direct ultrasound-guided percutaneous thrombin injection.


Pseudoaneurysm Compression



  • Small pseudoaneurysms
  • Long accessible necks (superficial)
  • Intact overlying skin
  • Patients not on anticoagulants

Direct Percutaneous Thrombin Injection



  • Almost all patients with the exception of uncommon contraindications (see below)

Contraindications


Pseudoaneurysm Compression


Poor candidates for compression represent ~10% of all patients and 50% of intent-to-treat technical failures.



  • Pain intolerance/painful pseudoaneurysms (25–34% of failures)
  • Morbid obesity (13% of failures)
  • Large pseudoaneurysms obliterating adjacent vascular structures (19% of failures)
  • Associated arteriovenous fistulous (AVF) component (1–2% of pseudoaneurysms)
  • Super-added infection or overlying skin breakdown
  • Unstable patients (2% of failures)

Direct Percutaneous Thrombin Injection


The contraindications to direct percutaneous thrombin injection therapy include



  • Infected pseudoaneurysms or overlying skin erosion/breakdown
  • Ruptured pseudoaneurysms
  • Associated AVF component
  • Associated ipsilateral deep venous thrombosis (DVT)
  • Previous treatment/exposure to bovine thrombin due to concerns for allergic reactions (relative contraindication)
  • Documented allergic reaction to bovine thrombin

Preprocedural Evaluation


Evaluate Prior Cross-Sectional Imaging



  • Look for radiographic findings to support the diagnosis of postcatheterization access pseudoaneurysm

    • Real-time gray-scale ultrasound

      • Hypoechoic lesion/mass in the groin (Figs. 22.1 and 22.2)


        image


        Fig. 22.1 (A) Doppler ultrasound evaluation of a femoral pseudoaneurysm gray-scale ultrasound image (top) and schematic sketch (bottom) of a femoral pseudoaneurysm (PsA) demonstrating a hypoechoic spherical structure, which pulsates in real-time. The pseudoaneurysm (PsA) is superficial (under 1 cm from the overlying skin). (B) Doppler image (top) and schematic sketch (bottom; arrow pointing to Doppler box) of the same pseudoaneurysm as in Fig. 22.1A, showing the typical yin–yang appearance with half of the pseudoaneurysm coloring in red (R), and the other half in blue (B). (C) Doppler image (top) and schematic sketch (bottom; arrow pointing to Doppler box) of the same pseudoaneurysm as in Figs. 22.1A and 22.1B. The image is along the longitudinal axis of the pseudoaneurysm neck (between arrowheads). Again, the typical yin–yang appearance with half of the pseudoaneurysm coloring in red (R), and the other half in blue (B). Coloring of the pseudoaneurysm neck is also in red and blue (R and B, respectively). The pseudoaneurysm neck measures at least 1.4 cm in length.




        image


        Fig. 22.2 (A) Gray-scale ultrasound image of a femoral pseudoaneurysm (PsA) (top) and schematic sketch (bottom) demonstrating a hypoechoic spherical structure, which pulsates in real-time. The image is along the longitudinal axis of the pseudoaneurysm neck (between arrowheads, and cursor crosses/calipers) and the femoral artery (FA). The pseudoaneurysm neck is also hypoechoic like the femoral artery and the pseudoaneurysm and measures 1.2 cm in length. (B) Doppler image (top) and schematic sketch (bottom; arrow pointing to Doppler box) of the same pseudoaneurysm as in Fig. 22.2A, showing the yin–yang appearance with half of the pseudoaneurysm coloring in red (R), and the other half would be colored blue (B). The image is along the longitudinal axis of the neck (N: in between arrowheads), which exhibits aliasing. Also note the injured femoral artery. (C) Doppler spectral waveform analysis sampling at the neck demonstrating bidirectional high velocity flow. In one direction (above the line), flow is in excess of 220 cm/second and in the other direction (below the line) flow is in excess of 120 cm/second.


      • Pulsatile hypoechoic mass especially when gentle pressure is applied by the transducer
      • A hypoechoic (vessel-like) neck communicating between the donor (mother) artery and the pseudoaneurysm (Fig. 22.2A)
      • Concentric layers of hematoma can be seen around the pseudoaneurysm (Fig. 22.3).


        image


        Fig. 22.3 (A) Direct percutaneous thrombin injection of a femoral pseudoaneurysm. Doppler spectral waveform analysis sampling at the neck of a pseudoaneurysm demonstrating bidirectional high-velocity flow. In one direction (above the line), flow is in excess of 60 cm/second and in the other direction (below the line) flow is in excess of 30 cm/ second. (B) Gray-scale ultrasound image (top) and schematic sketch (bottom) during needle placement into the pseudoaneurysm (PsA). The needle tip is seen in the hypoechoic pseudoaneurysm (PsA). Arrows point to the different layers of the pseudoaneurysm and the compression of surrounding tissue plains. (C) Doppler image (top) and schematic sketch (bottom; arrows pointing to Doppler box) of the same pseudoaneurysm as in Figs. 22.3A and 22.3B, demonstrating no color/flow in the pseudoaneurysm. This indicates successful treatment of the pseudoaneurysm. The arrowhead points to an adjacent vessel with color/flow within it.


    • Doppler ultrasound

      • This is the primary diagnostic modality.
      • A to-and-fro-flow (red and blue color) on Doppler is seen within the pseudoaneurysm (yin–yang sign) (Figs. 22.1B, 22.1C, 22.2B, and 22.4).


        image


        Fig. 22.4 (A) Doppler image (top) and schematic sketch (bottom; arrows pointing to Doppler box) showing the yin–yang appearance with half of the femoral pseudoaneurysm coloring in red (R), and the other half colored blue (B). Also note the injured femoral artery (FA). The area of mottled coloring (labeled as *) is due to motion from the pulsation and thrill/vibration of the adjacent pseudoaneurysm. (B) Doppler image (top) and schematic sketch (bottom; arrows pointing to Doppler box) of the same pseudoaneurysm (PsA) as in Fig. 22.4A. The image is along the longitudinal axis of the neck (between arrowheads), which exhibits blue coloring (B). (C) Doppler image (top) and schematic sketch (bottom; arrows pointing to Doppler box) of the same pseudoaneurysm as in Figs. 22.4A and 22.4B, demonstrating no color/flow in the pseudoaneurysm. This indicates successful treatment of the pseudoaneurysm. The arrowhead points to an adjacent vessel with color/flow within it.


      • Aliasing can be seen at the neck of the pseudoaneurysm (Fig. 22.2B) or varying colors (red and blue without aliasing) (Figs. 22.1C and 22.4B).
      • Doppler tracing wave form over the pseudoaneurysm neck typically shows high velocity bidirectional flow (Figs. 22.2C and 22.3A).
      • Complex pseudoaneurysms may have multiple lobulations or components to them.
      • Evaluate if there is an AVF component to the pseudoaneurysm (arterialization of the femoral vein, aliasing at the AVF site)
      • The donor or mother artery can be

        • Common femoral artery
        • Superficial femoral artery (most common)
        • Profunda femoris artery
        • Branches from the above branches such as circumflex iliac branches or circumflex femoral branches

    • Contrast-enhanced computed tomography (CT)

    • Contrast-enhanced magnetic resonance imaging (MRI)

      • This is not the primary diagnostic modality.
      • Contrast-filled out-pouching from the donor artery is seen. Concentric hematoma around the outpouching (pseudoaneurysm) with varying degrees of signal intensity depending on the age of the hematoma (usually acute and subacute phase)
      • Similar advantages to contrast-enhanced CT (see above)

      Stay updated, free articles. Join our Telegram channel

Mar 10, 2016 | Posted by in ULTRASONOGRAPHY | Comments Off on Management of Postcatheterization Pseudoaneurysm

Full access? Get Clinical Tree

Get Clinical Tree app for offline access