On radiographs multiple mainly sclerotic lesions are easily detected. The epiphyseal involvement is frequent in this lesion
High-grade osteoblastic osteosarcoma usually extensively sclerotic with low cellularity and diminished cytological anaplasia when compared to the less sclerotic areas of the tumor
Selected Bibliography
Bacci G, Fabbri N, Balladelli A, Forni C, Palmerini E, Picci P (2006) Treatment and prognosis for synchronous multifocal osteosarcoma in 42 patients. J Bone Joint Surg Br 88(8):1071–1075PubMedCrossRef
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