Pneumatosis of the Intestine

 Cystic or linear collections of gas in subserosal or submucosal layers of GI tract wall



• Pneumatosis intestinalis: Most common form of intramural gas, found in SB more often than colon

• Pneumatosis coli: Rounded collections of gas in distal colonic wall, usually asymptomatic finding




IMAGING




• Best imaging tool: MDCT with lung windows to detect intramural, intraperitoneal, and venous gas

• Pneumatosis of ischemic etiology
image Dilated bowel lumen (ileus), thickened wall, abnormal wall enhancement
– Ascites, may be of blood density (> 35 HU)

– ± pneumoperitoneum or pneumoretroperitoneum

– ± mesenteric or portal venous gas

• Portal venous gas is not always due to bowel infarction


TOP DIFFERENTIAL DIAGNOSES




• Bowel necrosis

• Post endoscopy

• Postoperative

• Medication induced

• Autoimmune disease

• Pulmonary disease

• Pseudopneumatosis


CLINICAL ISSUES




• Most common signs/symptoms
image Nonischemic causes: Patients are often asymptomatic

image Bowel ischemia: Nausea, abdominal pain, distension, melena, fever, vomiting, cough (depending on etiology)

• Treatment and prognosis depend on etiology

• Direct communication with clinical team is essential


DIAGNOSTIC CHECKLIST




• Important to recognize pneumatosis intestinalis, but significance depends on etiology and clinical setting

• Nonischemic causes of pneumatosis are usually asymptomatic, of little clinical significance

• Recognition of pneumatosis demands direct communication with clinical team to determine its likely etiology and optimal management

image
(Left) CT in a 50-year-old man on chronic steroid medication for psoriasis shows gas within the colon wall image, but the colon and SB show normal caliber. Note the free intraperitoneal gas image. This was a persistent asymptomatic finding attributed to medication.


image
(Right) CT shows extensive pneumatosis image throughout the SB. Bowel distention and ascites image help to confirm that the pneumatosis is likely on the basis of bowel ischemia, rather than one of the “benign” (nonischemic) causes of pneumatosis.

image
(Left) Axial CECT in a 75-year-old man who presented with abdominal pain and prior bowel ischemia demonstrates relatively subtle gas within the peripheral intrahepatic branches of the portal vein image.


image
(Right) Axial CECT in the same patient reveals extensive pneumatosis image within dilated segments of the bowel. Ascites is also noted image near the damaged bowel. The patient went to surgery for resection of the infarcted bowel.


TERMINOLOGY


Synonyms




Definitions




• Cystic or linear collections of gas in subserosal or submucosal layers of gastrointestinal (GI) tract wall

• Pneumatosis intestinalis: Most common form of intramural gas, found in small bowel more often than colon

• Pneumatosis coli: Rounded collections of gas in distal colonic wall, usually asymptomatic finding

• Pneumatosis is a descriptive sign, not a disease or diagnosis


IMAGING


General Features




• Best diagnostic clue
image Cystic or linear distribution of gas along bowel wall on CT


Radiographic Findings




• Radiography
image 


Fluoroscopic Findings




• Barium studies
image Pneumatosis intestinalis
– Mottled, bubbly, or linear collections of gas in bowel wall; feces-like appearance

– Dilated bowel loops ± thumbprinting

image Pneumatosis coli
– Radiolucent cysts resembling polyps, clustered along colonic contours

– Multiple large gas-filled cysts with scalloped defects in bowel wall, mimicking inflammatory pseudopolyps

– Concentric compression of colonic lumen by cysts

– Striking lucency of gas-filled cysts


CT Findings




• CECT
image Pneumatosis intestinalis
– Band-like: Bands or linear distribution of gas in affected bowel wall

– Linear or curvilinear shape

– Ischemic etiology: Dilated bowel lumen (ileus), thickened wall, abnormal enhancement
image Ascites, may be of blood density (> 35 HU)

image ± mesenteric arterial or venous thrombosis

– ± pneumoperitoneum or pneumoretroperitoneum

– ± mesenteric or portal venous gas
image Portal venous gas collects in liver periphery

image Biliary gas collects in central ducts near porta hepatis

– Nonischemic causes: Ileus and ascites are usually absent

image Pneumatosis coli
– Bubble-like: Isolated collections of air or clusters of cysts in left colonic wall

– Usually not accompanied by ileus, ascites, or clinical signs of acute abdominal process


Imaging Recommendations




• Best imaging tool
image Multiplanar CT with lung windows to detect gas

• Protocol advice
image CT with IV contrast at 3-4 mL/sec, 1.5-3 mm collimation
– 35-second image delay, repeat venous phase after 80 seconds

image Water for oral contrast facilitates CT angiography
– Multiplanar reformation is essential


DIFFERENTIAL DIAGNOSIS


Bowel Necrosis




• Ischemic enteritis, volvulus, necrotizing enterocolitis

• Mucosal damage → entry of bacteria (mainly enteric organisms) into bowel wall → gas in wall

• Necrotizing enterocolitis
image Premature or debilitated infants

image Affects ileum and right colon

image Feces-like appearance in right bowel

image Gas in intrahepatic branches of portal vein: Catastrophic sign

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Nov 16, 2016 | Posted by in GASTROINTESTINAL IMAGING | Comments Off on Pneumatosis of the Intestine

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