High-Grade Glioma
High-Grade Glioma Updated by Sarah McAvoy BACKGROUND What % of primary CNS tumors are malignant? ~40% of primary brain tumors are considered malignant. In adults, what is the most common…
High-Grade Glioma Updated by Sarah McAvoy BACKGROUND What % of primary CNS tumors are malignant? ~40% of primary brain tumors are considered malignant. In adults, what is the most common…
Optic Pathway Glioma Updated by Andrew J. Bishop BACKGROUND What is the typical age distribution of patients diagnosed with optic pathway gliomas (OPGs)? OPGs have a bimodal distribution with peaks…
Hemangioblastoma Updated by Sarah McAvoy BACKGROUND What is the typical age of presentation for hemangioblastoma? 20–50 yrs is the typical age of presentation for hemangioblastoma (primarily in young adults). Where…
General Central Nervous System Updated by Jingya Wang BACKGROUND What is the estimated annual incidence of primary CNS tumors in the U.S.? ~50,000–55,000 cases/yr of CNS tumors (per the National…
Intracranial Germ Cell and Pineal Tumors Updated by Nikhil G. Thaker BACKGROUND What are the 2 broad categories of germ cell tumors? Gonadal and extragonadal Pineal tumors represent what %…
Craniopharyngioma Updated by Andrew J. Bishop BACKGROUND What is the origin of craniopharyngioma? Epithelial tumor derived from Rathke’s pouch, the embryonic precursor to the anterior pituitary In what region of…
Neuroblastoma Updated by Jingya Wang Background What are the 3 types of neuroblastic tumors? 3 types of neuroblastic tumors: 1. Neuroblastoma (NB) 2. Ganglioneuroblastoma 3. Ganglioneuroma These tumors differ in…
Medulloblastoma Updated by Nikhil G. Thaker BACKGROUND Estimate the annual incidence of medulloblastoma (MB) in the U.S. What is its frequency relative to other CNS tumors in children? ~500 cases/yr…
Retinoblastoma Updated by Vinita Takiar BACKGROUND What is the incidence and median age for presentation of retinoblastoma (RB)? 250–300 cases/yr of RB; 95% <5 yo (1 yo for familial, 2…
Ependymoma Steven H. Lin, Ori Shokek, and Updated by Mark Edson BACKGROUND In children and adults, what % of brain tumors are ependymomas? Children: 5% (3rd most common childhood CNS…