Physics of Cardiovascular OCT
Fig. 2.1 Basic OCT setup, with a beam splitter (BS) separating the light into the sample arm towards the tissue, and the reference arm towards the mirror, respectively. The plots…
Stent Thrombosis
Fig. 11.1 Histology and OCT. (a) and (b) Magnified histology sections (Movat pentachrome stain) and corresponding OCT image (c, d) of a specimen of stented coronary artery with implant duration…
Basic Interpretation Skills
Fig. 4.1 Ruptured thin-capped fibroatheroma. Consecutive OCT frames in a 73-year-old male patient presenting with anterior STEMI (ST elevation myocardial infarction). After thrombus aspiration, adequate image quality could be obtained….
The Development of OCT
Fig. 1.1 Optical coherence tomography (OCT) generates cross-sectional or three dimensional images by measuring the magnitude and echo time delay of light. Data is composed of axial scans (A-scans) which…
Insight into Pathogenesis of Acute Coronary Syndrome
Fig. 7.1 Atherosclerotic lesions with luminal thrombi. (a) Ruptured plaques are thin fibrous cap atheromas with luminal thrombi (Th). These lesions usually have an extensive necrotic core (NC) containing large…
Intravascular OCT Imaging Artifacts
Fig. 5.1 Ghost lines. OCT image with ghost lines between outer catheter (red dotted line) and blue arrow 5.2.3 Residual Blood from Incomplete Lumen Flushing Blood must be completely flushed…
Clinical Presentations and Coronary Plaque Characteristics
Fig. 6.1 Representative OCT images of coronary plaque characteristics. (a) Fibrous plaque; (b) Thin-cap fibroatherma: fibrous cap <65 μm (arrows) covering a lipid-rich plaque; (c) Calcification (asterisks); (d) Neovascularization (arrows);…
Histology Validation of OCT Images
Fig. 3.1 The layered structure of the coronary wall imaged by optical coherence tomography (OCT). This OCT image demonstrates visualization of the intima, media and adventitia. The bright-dark-bright, three-layered appearance…
Future Development
Macro trend Potential consequences Emphasis on cost effectiveness of PCI Earlier triage via non-invasive testing Selective use of invasive diagnostics Lower disposable costs Emphasis on functional assessment Preference for rapid,…
Bioabsorbable Stent
Scaffold Manufacturer Design Drug-elution Strut thickness (μm) Resorption time (months) Polymeric Igaki-Tamai Kyoto medical Zigzag hoops No 170 24–36 BVS1.0 Abbott vascular Circumferential hoops Everolimus 150 24–48 BVS1.1 Abbott vascular…
