Data Processing and Analysis for Mass Spectrometry Imaging
Fig. 1 A histogram of peak intensity based on the statistical analysis of 3,450 spectra recorded from a tissue section of mouse brain. Inset, percentage of the original data which…
Fig. 1 A histogram of peak intensity based on the statistical analysis of 3,450 spectra recorded from a tissue section of mouse brain. Inset, percentage of the original data which…
Fig. 1 Representative molecular imaging methods. Reprinted from [31] with permission from Springer Science Efforts to improve the ionization process in conventional MALDI-IMS are ongoing. Strategies to improve this process…
Fig. 1 MSI analysis workflow: (a) The first step is sample preparation, which requires minimal or sometimes no sample preparation; (b) data acquisition includes the steps of desorption/ionization, mass analysis,…
Fig. 1 Schematic draw of an electrochemical etching cell for SALDI substrate preparation. Adapted with permission from ref. 12 3. Electrochemically etch the Si chip in the pSi etching…
Fig. 1 Coordinate acquisition for single-cell ablation in an optical microscope image of L. longiflorum leaf adaxial epidermis. (a) Microscope image of L. longiflorum leaf adaxial epidermis is taken. (b)…
Fig. 1 (Top) Ion source and (bottom) vacuum chamber for laser desorption postionization mass spectrometer (LDPI-MS) instrument. Ion source shows only desorption laser, as ionization lasers come out of page…
Fig. 1 Schematic drawing of an electrochemical etching cell for porous Si preparation. Adapted with permission from ref. 7 7. MALDI standard solution and matrix: Nominally 0.01 mM of…
Fig. 1 (a) Schematic of the laser ablation sample transfer system for MALDI imaging. MALDI images of mouse brain sections prepared by IR laser ablation transfer to (b) matrix-pre-coated target…
Fig. 1 (a) Graphic representation of the ELDI setup. The sample deposited on the stainless steel plate was positioned on the mobile sample stage and irradiated with a pulsed laser…
Fig. 1 Electron micrographs of silicon-based nanostructure surfaces used in NIMS experiments. A unique feature of these surfaces is that they are UV-absorbing thermal insulators with a large surface area,…