Fig. 9.1 Representative FDG-PET images of AD patient. (a) Tomography, (b) 3D-SSP, and (c) 3D-SSP Z-score images show hypometabolism in the parietotemporal association cortex, posterior cingulate, and precuneus Reduction in…
Fig. 10.1 Chemical structures of tau PET radiotracers 10.3.1 Naphthylethylidene Derivative [18F]FDDNP was developed as a nonselective PET tracer for SPs and NFTs in the brain. Autoradiography of AD brain…
Fig. 6.1 Schematic description of ASL perfusion imaging. Labeled images are obtained when labeled arterial blood with inverted magnetization reaches the brain tissue in the imaging plane, while control images…
Fig. 5.1 Analysis using the tract-based method. Tractographies were drawn using diffusion-weighted images (EPI imaging: TR/TE, 2300/122 ms; b = 1000 s/mm2; 6-axis encoding). Tractographies of the inferior occipitofrontal fasciculus…
Fig. 8.1 Schema of resting-state networks. (a) medial visual-related network, (b) lateral visual-related network, (c) auditory-related network, (d) sensorimotor network, (e) default mode network, (f) executive control network, (g, h)…
Fig. 2.1 Hypothetical model of dynamic biomarkers and clinical disease stage of AD. Modified from Sperling et al. [5] Based on these advances in research findings, in 2011, the criteria…
