Quality Assurance and Commissioning
(1) Fig. 4.1 Measurements of depth dose for probe only and applicator, with best fit lines overlaid Baseline readings are also acquired during factory calibration for the IRM feedback monitor…
Intra Operative Radiotherapy in Developing Countries: Experience with TARGIT from University of Dammam, Saudi Arabia
Fig. 16.1 Increase in the number of breast cancer patients at the King Fahd Hospital, University of Dammam Fig. 16.2 Age distribution of breast cancer patients at the King Fahd…
Quality Assurance and Training of Targeted Intraoperative Radiotherapy: Establishment of the TARGIT Academy
Fig. 19.1 Inauguration of TARGIT Academy at the Royal Free Hospital, London with the faculty from the UCL and University of Mannheim and participants 19.2.1 Theory Days and Hands-on Training…
Treating Patients with TARGIT
Inclusion criteria Exclusion criteria Age ≥45a years No informed consent T1–2 (≤2.0a cm; mammography, ultrasound) Non-compliance cN0 (examination, ultrasound) Age <45a years Histopathology: ductal-invasive Tumour size >2.0a cm Unifocal cN+…
Cosmetic Outcome Following TARGIT
Fig. 10.1 Examples of assessment using BCCT.core Although patient-reported outcome measures are increasingly used and quality of life is a key measure of clinical effectiveness, the measures used fall short…
Targeted Intraoperative Radiotherapy and Persistent Pain After Treatment
EBRT IORT p (95 % CI) Total No. (%) 112 (47.1) 126 (52.9) 238 Non-responders 4 0 4 Age, years (mean) 65.74 (SD 6.17) 64.76 (SD 6.45) 0.23 (−0.64–2.60)…
Mechanism of Action of TARGIT
Fig. 2.1 TARGIT impairs the proliferative activity of wound fluids from breast cancer patients. This figure shows the colony formation assay. In (a), MCF-7 breast cancer cells were included in…
Quality of Life and Late Radiation Toxicity
Matched pair analysis (I) EBRT + boost (III) Mannheim TARGIT-A QoL trial (II) IORT EBRT IORT-EBRT IORT-boost EBRT-boost Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) General pain I…
Follow-Up Findings in the Tumour Bed After IORT – What the Radiologist Needs to Know
Fig. 8.1 Mammogram (a) of a patient with breast cancer who had received breast-conserving therapy and IORT as a boost 5 years previously. A well-circumscribed and partially calcified mass of…
Targeted Intraoperative Radiotherapy: Concept and Review of Evidence in Breast Cancer
Fig. 1.1 Rapid attenuation of the radiation dose as the distance increases The mechanism of action of this approach is described in detail later in this textbook. In brief, a…
