Hepatic Variants
Technical Aspects Diagnostic imaging of the hepatobiliary system, with multidetector computed tomography (MDCT) and magnetic resonance imaging (MRI), plays a major role in hepatobiliary surgery, helping to choose the best…
Cholestatic Hepatic Disorders
Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are the two most common and well-characterized primary cholestatic disorders. In contrast to pathologic processes derived primarily from hepatocellular dysfunction, such…
Hepatic Veno-occlusive Diseases
The hepatic veno-occlusive diseases are a heterogeneous group of circulatory disorders characterized by obstruction of hepatic venous outflow at the sinusoidal or postsinusoidal levels. These disorders uniquely manifest portal hypertension…
Fatty Liver Disease
Etiology Fatty liver is a generic term that refers to the accumulation of lipids within hepatocytes. This chapter focuses on nonalcoholic fatty liver disease (NAFLD), the most common form of…
Hepatic Iron Overload
Etiology Hepatic iron overload is a generic term that refers to the nonphysiologic accumulation of iron within the hepatic parenchyma. The most clinically significant cause of hepatic iron overload is…
Benign Focal Lesions
Etiology Although benign hepatic tumors have been classified into several histiotypes according to their cell of origin (i.e., hepatocytes, biliary epithelium, or mesenchymal cells), our focus in this discussion is…
Malignant Focal Lesions
Etiology Malignant liver tumors can be classified either by cell of origin as hepatocellular, cholangiocellular, or mesenchymal or by site of origin as primary or secondary. This chapter will describe…
Hepatic Storage Disorders
The hepatic storage disorders are genetic conditions characterized by the accumulation of toxic substances within either hepatocytes or the hepatic extracellular matrix. This deposition causes secondary tissue damage, which may…
Colonic Vascular Lesions
Etiology Vascular lesions of the colon are an important medical problem and have now been recognized as a significant cause of gastrointestinal bleeding. They can be solitary or multifocal, benign…
Colon Cancer and Screening Strategies
Etiology The causes of the development of colorectal carcinoma and its precursor lesion, the colonic adenoma, are multifactorial and include both genetic predisposition and environmental insults. Risk factors for colorectal…
