Imaging of the Central Skull Base
The central skull base (CSB) constitutes a frontier between the extracranial head and neck and the middle cranial fossa. The anatomy of this region is complex, containing most of the…
Brain Irradiation: Effects on Normal Brain Parenchyma and Radiation Injury
Radiation therapy is a major treatment modality for malignant and benign brain tumors. Concerns of radiation effects on the brain tissue and neurocognitive function and quality of life increase as…
Diffusion Imaging for Therapy Response Assessment of Brain Tumor
Advanced imaging provides insight into biophysical, physiologic, metabolic, or functional properties of tissues. Because water mobility is sensitive to cellular homeostasis, cellular density, and microstructural organization, it is considered a…
Therapeutic Advances in Malignant Glioma: Current Status and Future Prospects
This article reviews the current status and trends in the treatment of primary gliomas, focusing predominantly on glioblastoma. It also discusses the current standard of care and new targeted agents…
Advanced MRI: Translation from Animal to Human in Brain Tumor Research
Advanced magnetic resonance imaging (MRI) techniques, such as magnetic resonance spectroscopy, diffusion MRI, and perfusion MRI, allow for a diverse range of multidimensional information regarding brain tumor physiology to be…
Presurgical Mapping of Verbal Language in Brain Tumors with Functional MR Imaging and MR Tractography
Functional magnetic resonance (fMR) imaging and diffusion MR tractography have emerged as valuable tools in the evaluation of verbal language in brain tumor patients, and have changed the way neurosurgeons…
Intraoperative Mapping for Tumor Resection
This article describes the rationale, indications, and modality for intraoperative brain mapping for safe and effective surgical removal of tumors located within functional brain areas. Intraoperative mapping refers to a…
Quantitative Sodium MR Imaging and Sodium Bioscales for the Management of Brain Tumors
Treatment of high-grade primary brain tumors is based on experience from multicenter trials. However, the prognosis has changed little in 3 decades. This suggests that there is a fundamental oversight…
Magnetic Resonance Perfusion and Permeability Imaging in Brain Tumors
Recent evidence suggests that vascular permeability and the presence of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) are important mediators of brain tumor growth in addition to angiogenesis. Perfusion and…
