Fig. 14.1 Age distribution of volunteers who revealed neurological abnormalities (e.g., pathological reflex, sensory or motor abnormalities) by physical examination. Of the 685 volunteers (dark + light green), 81 revealed…
Fig. 13.1 (a) MRI (T1) images of bvFTD. The axial (left) and coronal (right) images demonstrate frontotemporal atrophy. (b) The result of VSRAD analysis (normal healthy volunteers vs. bvFTD individual)….
Fig. 12.1 A comparison of z-scores between AD and DLB using VSRAD Among subcortical structures, atrophy of the substantia innominata (including the nucleus basalis of Meynert) [11] and dorsal midbrain…
Fig. 1.1 Prevalence of early-onset dementia in terms of 5-year age strata Oddly, the response rate was exactly the same in two surveys in Japan [1, 2]. It is also…
Fig. 3.1 Subfield segmentation from high-resolution T2-weighted image. Automatic volumetry is possible in hippocampal subfields and adjacent cortical subregions. CA cornu ammonis, DG dentate gyrus, SUB subiculum, ERC entorhinal cortex,…
Fig. 16.1 Relationship between method of PET scanning and image quality and their possible effects on diagnostic capability. NEC noise equivalent count, PVE partial volume effect 16.3.2 Injection Activity and…
Fig. 15.1 Example of differences between MR image qualities. (a) Good quality image, (b) blurring artifact around frontal gyrus, (c) poor SNR Moreover, several preprocessing steps such as geometrical distortion…
Fig. 9.1 Representative FDG-PET images of AD patient. (a) Tomography, (b) 3D-SSP, and (c) 3D-SSP Z-score images show hypometabolism in the parietotemporal association cortex, posterior cingulate, and precuneus Reduction in…
Fig. 10.1 Chemical structures of tau PET radiotracers 10.3.1 Naphthylethylidene Derivative [18F]FDDNP was developed as a nonselective PET tracer for SPs and NFTs in the brain. Autoradiography of AD brain…
Fig. 5.1 Analysis using the tract-based method. Tractographies were drawn using diffusion-weighted images (EPI imaging: TR/TE, 2300/122 ms; b = 1000 s/mm2; 6-axis encoding). Tractographies of the inferior occipitofrontal fasciculus…
