linear accelerator machines
Megavoltage linear accelerator machines The workhorse of modern radiotherapy is the linear accelerator which owes its development to the pioneers who worked to produce higher energy beams than the kilovoltage…
Radiotherapy beam production
General Kilovoltage x-ray beam machines Tube stand High voltage circuits Collimation Beam energy Control of output Skin and eye shielding Calibration of dose output Megavoltage linear accelerator machines General layout…
protection, waste and regulations
Chapter 4 where the reader will find in particular sections dealing with ARSAC for the administration of radioactive substances, the transport of substances, the statutory instruments governing the general use…
monoclonal antibodies in non-Hodgkin’s lymphoma
24] is a relatively recent introduction. RIT has been proven to be effective in follicular non-Hodgkin’s lymphoma (NHL) and clinical trials are continuing in this and other forms of NHL,…
effects of radiation
Figure 4.1) details the various biological effects that radiation may cause resulting from the absorption of energy associated with the radiation. As will be seen later, different areas of the…
m-IBG therapy in neuroendocrine disease
21] and in neuroblastoma in 1984 [22]. Before treatment, any drugs known to interfere with the uptake and/or retention of 131I m-IBG must be withdrawn (EANM). A thyroid blocking agent…
and intracavitary treatments
Table 7.1), and the usual activity per knee joint is 185 MBq. Rhenium-186 (186Re) and erbium-169 (169Er) are mentioned for completeness, as they are used outside the UK and discussed in…
in the treatment of refractory myeloproliferative disease
12]. Treatment regimens vary and are a matter for clinical judgment, with typical activities in the range 150–250 MBq. The EANM Guideline suggests two regimens in current use, based on using…
Therapy with unsealed radionuclides
Introduction Iodine-131 in the treatment of thyroid disease Thyrotoxicosis Thyroid tumours Phosphorus-32 in the treatment of refractory myeloproliferative disease Intra-articular and intracavitary treatments Palliation of bone pain Iodine-131 m-IBG therapy…
