Interventions Dose (mg) Active comparator Follow-upmonths ∆LDL-C(%) ∆HDL-C(%) Target vessels Referencenumber Simvastatin 5–20 Diet management 3 −29.5 +14.9 Aorta, carotid arteries [19] Atorvastatin 20 Atorvastatin 5 mg 6 −38.5 +13.5…
Fig. 11.1 Normal trileaflet aortic valve in parasternal long-axis view (a) and parasternal short-axis view (b). Severe calcific aortic valve disease is shown at the bottom panels (c, d) from…
Fig. 8.1 Types of fluorescent imaging agents 8.3.2 Fluorescent Protein Information about various biological processes and functions (e.g., specific cell types, enzymatic reactions, molecule distribution) can be directly obtained…
Fig. 6.1 Representations of well-characterized oxidation-specific epitopes and antibodies. Oxidation-specific antibodies recognize protein and lipid epitopes on oxidized LDL (OxLDL). These epitopes include malondialdehyde (MDA), phosphocholine-containing oxidized phospholipids (PC-OxPL), and…
Method Advantages Disadvantages Epifluorescence Fast Poor axial and lateral resolution Lower photobleaching than confocal Limited to thin tissues Limited control of excitation wavelength Spinning disk confocal (SDCM) Fast Low excitation…
Fig. 5.1 Molecular imaging of endothelial VCAM-1 expression. A VCAM-1-targeted NIRF probe shows co-localization with VCAM-1 staining by immunohistochemistry in mouse aorta. This signal is also associated with CD31 expression,…
Fig. 3.1 Macrophage imaging in hyperlipidemic rabbits 6 months after balloon injury of the aorta. (a) MR images taken 72 h after intravenous administration of the USPIO MION-47. MION-47 administration…
Chapter 16 Evaluation of Intracardiac Masses Elisa Zaragosa-Macias, Edward A. Gill Introduction Perhaps no finding on echocardiography creates a bigger diagnostic challenge than the presence of an intracardiac mass. This…
Chapter 7 Planning and Guiding Mitral Valve Repair Gary S. Mak, Judy Hung Introduction Mitral valve prolapse is the most common structural cause of chronic mitral regurgitation leading to surgery…
Chapter 17 Use of the Cropping Tool to Show Structures of Interest Alicia A. Bourne, Terese Tognazzi-Evans, Rachel Karl, Denise McRee, Eric J. Sisk, Edward A. Gill Summary This chapter…
