Radiation Protection
Radiation source Energy Radium-226 830 keV Caesium-137 662 keV Iridium-192 380 keV Electron linacs 4–12 MeV INTRABEAM 50 kV Values are the average energy of the radionuclides (Khan 2003), or…
Patient Selection and Information
Inclusion criteria Exclusion criteria Age ≥45 yearsa No informed consent T1-2 (≤3.5 cma; mammography, ultrasound) Non-compliance cN0 (examination, ultrasound) Age <45 yearsa Histopathology: ductal-invasive Tumour size >3.5 cm Unifocal cN+…
Intraoperative Radiotherapy with Low-Energy Photons in Rectal Cancer Recurrence
Fig. 14.1 Visualisation of the surgical bed. The surgeon checks the fit of the applicator to the dimensions of the tumour cavity Fig. 14.2 The applicator on an arm of…
Quality Assurance and Commissioning
(1) Fig. 4.1 Measurements of depth dose for probe only and applicator, with best fit lines overlaid Baseline readings are also acquired during factory calibration for the IRM feedback monitor…
Intra Operative Radiotherapy in Developing Countries: Experience with TARGIT from University of Dammam, Saudi Arabia
Fig. 16.1 Increase in the number of breast cancer patients at the King Fahd Hospital, University of Dammam Fig. 16.2 Age distribution of breast cancer patients at the King Fahd…
Treating Patients with TARGIT
Inclusion criteria Exclusion criteria Age ≥45a years No informed consent T1–2 (≤2.0a cm; mammography, ultrasound) Non-compliance cN0 (examination, ultrasound) Age <45a years Histopathology: ductal-invasive Tumour size >2.0a cm Unifocal cN+…
Quality Assurance and Training of Targeted Intraoperative Radiotherapy: Establishment of the TARGIT Academy
Fig. 19.1 Inauguration of TARGIT Academy at the Royal Free Hospital, London with the faculty from the UCL and University of Mannheim and participants 19.2.1 Theory Days and Hands-on Training…
Cosmetic Outcome Following TARGIT
Fig. 10.1 Examples of assessment using BCCT.core Although patient-reported outcome measures are increasingly used and quality of life is a key measure of clinical effectiveness, the measures used fall short…
Quality of Life and Late Radiation Toxicity
Matched pair analysis (I) EBRT + boost (III) Mannheim TARGIT-A QoL trial (II) IORT EBRT IORT-EBRT IORT-boost EBRT-boost Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) General pain I…
Mechanism of Action of TARGIT
Fig. 2.1 TARGIT impairs the proliferative activity of wound fluids from breast cancer patients. This figure shows the colony formation assay. In (a), MCF-7 breast cancer cells were included in…
