Normal Myelination
MRI is currently the best imaging modality to assess myelin maturation in the human brain. Myelin is the insulator for nerves and is present in both the peripheral nervous system…
Magnetic Resonance Spectroscopy in Common Dementias
Neurodegenerative dementias are characterized by elevated myoinositol and decreased N -acetylaspartate (NAA) levels. The increase in myoinositol seems to precede decreasing NAA levels in Alzheimer’s diseases. NAA/ myo -inositol ratio…
Hypoxic-Ischemic Injuries
Hypoxic ischemic injuries are a very common clinical situation in the pediatric population. This article focuses on the metabolic signature of hypoxic ischemic injuries and metabolic indicators of prognosis. Key…
Pediatric Brain Tumors
Pediatric brain tumors are the most common solid tumor of childhood. This article focuses on the metabolic signature of common pediatric brain tumors using MR spectroscopic analyses. Key points •…
Adult Brain Tumors
Proton magnetic resonance spectroscopy (H-MRS) may be helpful in suggesting tumor histology and tumor grade and may better define tumor extension and the ideal site for biopsy compared with conventional…
MR Spectroscopy in Brain Infections
Infection of the central nervous system can be life-threatening and hence requires early diagnostic support for its optimal management. Routine definitive laboratory diagnostic tests can be time-consuming and delay definitive…
Magnetic Resonance Spectroscopy in Metabolic Disorders
Magnetic resonance spectroscopy (MRS) is a powerful clinical tool for investigating the metabolic characteristics of neurologic diseases. Proton ( 1 H)-MRS is the most commonly used and widely available method….
1H Magnetic Resonance Spectroscopy in Multiple Sclerosis and Related Disorders
Proton magnetic resonance spectroscopy ( 1 H-MRS) is an unconventional technique that allows noninvasive characterization of metabolic abnormalities in the central nervous system. 1 H-MRS provides important insights into the…
The Use of Magnetic Resonance Spectroscopy in the Evaluation of Epilepsy
Magnetic resonance spectroscopy (MRS) is indicated in the imaging protocol of the patient with epilepsy to screen for metabolic derangements such as inborn errors of metabolism and to characterize masses…
Proton Magnetic Resonance Spectroscopy
Magnetic resonance spectroscopy (MRS) provides information on neuronal and axonal viability, energetics of cellular structures, and status of cellular membranes. Proton MRS appeals to clinicians and scientists because its application…
