KEY POINTS • Metabolic diseases are independently associated with increased CVD risk. • SPECT MPI is limited by soft-tissue attenuation in obese individuals; however, imaging techniques including prone and gated…

KEY POINTS • Nuclear imaging with PET and SPECT can be used to study the biologic mechanisms that underlie high-risk atherosclerotic plaque features. • High-risk plaque features targeted by nuclear…

KEY POINTS • Chest pain is one of the most common ED chief complaints and represents approximately 5% of all ED visits. • Although triage of low-risk and high-risk patients…

KEY POINTS • Radionuclide imaging artifacts are common and can lead to false positive results, decreasing the accuracy of the study. • SPECT and PET imaging artifacts are related to…

KEY POINTS • Exercise testing with MPI is preferred for evaluating symptomatic patients with known CAD to establish a link between symptoms and perfusion defects and for optimal risk stratification….

KEY POINTS • Coronary revascularization with CABG or PCI is a palliative intervention strategy associated with residual risks and the need for both secondary prevention lifestyle and medical therapies and…

KEY POINTS • Preoperative risk stratification should be a comprehensive assessment with careful evaluation of active cardiac conditions, clinical risk factors, and planned surgical intervention. • Noninvasive ischemic evaluation should…

KEY POINTS • The assessment of patients with new-onset stable chest pain includes a detailed history assessment and ECG. • The current risk scores tend to overestimate the risk for…

KEY POINTS • A key physiologic attribute that defines the quality of a MPI agent is defined by the relationship between the tracer uptake and MBF. A linear relationship maximizes…

KEY POINTS • Accurate quantitative MBF quantification requires an understanding of the technical capabilities of the instrumentation and quantitative software used to make the measurements. • Quality control of MBF…