Fig. 1 Magnetic resonance imaging (MRI) demonstrating extracapsular spread on axial image (green arrow) (a) and seminal vesicle involvement on coronal image (orange arrows) (b) Some patients may not be optimal…

Fig. 1 11C-Choline PET/CT showing increased uptake on the left side corresponding to radio-recurrent prostate cancer 4 Surgical Technique of Salvage Prostatectomy Radical prostatectomy is the local salvage treatment modality with…

Reference No. Pts Dose/fx size/# fxs EQD2 α/β = 1.5 Gy (tumor) (Gy) EQD2 α/β = 3 Gy (late effects) (Gy) Med F/U (mos) Risk class % 5-year FFBF Fonteyne et al. (2012) 113 55 Gy/3.4 Gy/16 fx…

Fig. 1 Cause-specific survival in patients with and without prostate- specific antigen failure (adopted from Kwan et al. (Kwan et al. 2004)) Fig. 2 Overall survival in patients with and without prostate-…

Fig. 1 Examples of different types of focal therapy. Ultra-focal therapy refers to treating a a specific target lesion or b multiple target lesions with a margin. Hemi-focal therapy refers to…

  Low risk Intermediate risk High risk Seattle Zelefsky et al. (1998) (all factors) T1-2 + GS ≤6 + PSA ≤10 (one factor) >T2 / GS ≥7 / PSA >10…

Trial/update n Risk Groups (%) Dose Treatment modality End point Hormonal therapy Boston Zietman et al. (2010) 393 Low Intermediate High 58  37  5  70.2 Gy vs 79.2 Gy 3D 50.4 Gy/1.8 Gy +…

Fig. 1 Normal distribution of 18F-choline 2.2 11C-Acetate Acetate is absorbed by cells and converted into acetyl-CoA. In this form, it can be involved into two different metabolic pathways: either anabolic…