Fig. 33.1 [123I]FP-CIT SPECT scan obtained (3 h after injection) in a 21-year-old healthy female control (left side) and in a 78-year-old healthy female control (right side). Striatal binding of…

Fig. 28.1 Decreasing striatal 123I-β-CIT binding over time in patients with APS. Striatal 123I-β-CIT binding in individual patients with atypical parkinsonian syndromes, including MSA (circles), PSP (squares), and CBD (triangles),…

Fig. 45.1 Typical examples of 11C-NMSP microPET imaging in various conditions. Coronal and axial sections of rat brain are shown. White cross markers in the coronal and axial sections indicate…

In contrast to MRI, which gives a pictorial representation of body cross sections, MRS yields a “spectrum” of peaks at different radiofrequencies (“chemical shifts”). The chemical shift that results from…

Fig. 16.1 FDG-PET scan showing serial axial images and surface-rendered z-score maps of significant hypometabolism relative to a normal control database showing selective mesial occipital hypometabolism in a patient with…

Scan type Radiotracer Participants Main findings Reference SPECT 123I-IMP 1 ALS-FTD 1 HC Marked loss of frontotemporal uptake Sawada et al. (1988) 17 ALS (1 FU after 9 months); 15…

Fig. 48.1 Ligand-gated ion channels are probably the most relevant targets for general anaesthetics. A dark green or pink spot indicates significant potentiation or inhibition, respectively, of agonist actions at…

Fig. 19.1 Example of mediastinal and cardiac region of interest (ROI) on anterior planar image. The left ventricular ROI was drawn including the ventricular cavity (H), and a rectangular ROI…

Authors N Diagnosis Time since insult (month(s)) Main findings Levy et al. (1987) 7 UWS 1–72 60 (53–67 %) decrease in metabolism DeVolder et al. (1990) 7 UWS 1–4 53…

Fig. 11.1 In the SPM analysis the coloured clusters label the significantly lower α4β2*-nAChR availability by assessment of the 2-FA distribution volume ratio (2-FA-DVR) in AD and MCI patients (pilot…