Fig. 1 Schematic representation of strategies used for microproteomics analysis using Liquid MicroJunction (LMJ) . The upper panel shows methods to define regions of interest (ROIs) according to highlighted regions,…
Fig. 1 Image displaying (a) alignment of mouse optic nerve tissue along hypodermic needle after dissection, (b) displaying initial freezing process where the lower portion of the hypodermic needle is…
Fig. 1 Cutting apparatus used for longitudinal sectioning of hair samples. (a) Image of the in-house built cutting apparatus and (b) schematic of the cutting apparatus 2. Following decontamination,…
Fig. 1. (a) Stereotaxic frame used to freeze the carcass while maintaining spinal alignment. (N.B. the array of holes in each side permits the free flow of the hexane/dry ice…
Fig. 1 Chemical structures of nonionic surfactants; (a) n-Octyl ß-d-glucopyranoside (OcGlu), (b) N-Octyl 1-thio-ß-d-glucopyranoside (OcThio), (c) N-Decyl ß-d-maltoside (DDM), (d) N-Octanoyl-N-methylglucamin (MEGA-8) Concentrations of OcGlu higher than 0.1% (up to…
Fig. 1 Sample stocking procedure for ITO glass slides with mounted tissue 3.1.2 Tissue Preparation for MALDI-MSI 1. Following removal from the freezer, the ITO glass slides with mounted…
© Springer Science+Business Media LLC 2017Laura M. Cole (ed.)Imaging Mass Spectrometry Methods in Molecular Biology161810.1007/978-1-4939-7051-3_16 16. The Future in Disease Models for Mass Spectrometry Imaging, Ethical Issues, and the Way Forward Rebecca E. Day1 and Ieva Palubeckaite1…
Fig. 1 Deposition of discrete matrix spots onto a fingermark sample and subsequent MALDI MS profiling showing how chemical differences can be observed between the selected areas 3.3.2 Spraying…
Benign thyroid nodules Malignant thyroid nodules Follicular adenoma (FA) Conventional variant papillary thyroid carcinoma (cvPTC) Hyperplastic (Hp) Follicular variant papillary thyroid carcinoma (fvPTC) Hashimoto’s thyroiditis (HT) Uncertain malignant potential (UMP)…
Fig. 1 Basic workflow of an imaging experiment with key focus areas; sample collection, sample preparation, choice of organic matrix , mode of application, and finally choice of mass spectrometer…
