Fungal Infections
Etiology Fungal infections of the chest can be divided into two groups based on pathogenesis. The first group is composed of endemic fungi, including Histoplasma capsulatum, Coccidioides immitis, Blastomyces dermatitidis,…
Human Immunodeficiency Virus Infection
Etiology Since the recognition of human immunodeficiency virus (HIV) infection as the cause of acquired immune deficiency syndrome (AIDS) in the 1980s, many changes have occurred in the demographics, complications,…
Lung Cancer: Radiologic Manifestations and Diagnosis
Etiology Lung cancer arises when cells lining the bronchi or peripheral airways undergo neoplastic change in response to an inciting agent or agents. The most common and well-recognized cause of…
Pulmonary Carcinoma Staging
Schemes for Staging The most widely used scheme for staging non–small cell lung cancer (NSCLC) is the TNM classification. A variety of alterations in this scheme have been made to…
Pulmonary Tuberculosis
Overview Etiology, Prevalence, and Epidemiology Tuberculosis (TB) is a chronic recurrent contagious infection caused by Mycobacterium tuberculosis. M. tuberculosis is an aerobic, nonmotile, non–spore-forming rod that is highly resistant to…
Inflammatory Pseudotumor
Etiology, Prevalence, and Epidemiology Inflammatory pseudotumor, also known as inflammatory myofibroblastic tumor, is a quasineoplastic lesion that clinically and radiologically tends to mimic a malignant neoplasm and that histologically consists…
Neuroendocrine Hyperplasia, Pulmonary Tumorlets, and Carcinoid Tumors
Neuroendocrine Hyperplasia and Pulmonary Tumorlets Etiology, Prevalence, and Epidemiology Normal lung tissue contains scattered neuroendocrine (Kulchitsky) cells within the bronchial and bronchiolar epithelium. These cells play a role in the…
Pulmonary Hamartoma
Etiology, Prevalence, and Epidemiology Pulmonary hamartomas are benign neoplasms, probably derived from bronchial wall mesenchymal cells. Hamartomas are the most common benign pulmonary neoplasm and account for about 8% of…