Tracer Kinetic Modelling
Fig. 3.1 Uptake of the NK1 receptor ligand [11C]R116301 in a normal volunteer with (left) a total uptake image (60–90 min after injection) and (right) a parametric image on non-displaceable…
Fig. 3.1 Uptake of the NK1 receptor ligand [11C]R116301 in a normal volunteer with (left) a total uptake image (60–90 min after injection) and (right) a parametric image on non-displaceable…
Fig. 5.1 Schematic overview of MRI and PET imaging potential 5.1 MRI Basics 5.1.1 Nuclear Magnetic Resonance (NMR) (Gibby 2005; Pooley 2005.; McRobbie 2003; NessAiver 1997; Elster and Burdette 2001)…
Fig. 50.1 Axial 2-deoxy-2(18F)-fluoro-d-glucose PET scan in a child with intractable temporal lobe epilepsy and normal MRI. EEG changes were occasionally bilateral or equivocal. PET scan showed hypometabolism in the…
Target Related disease Tracers (human application) Binding mechanism TSPO MS, AD, stroke, PD, HD, schizophrenia [11C]PK11195, DAA, and PBR derivatives Antagonist GABA Stroke [11C]Flumazenil Antagonist Dopaminergic system PD, HD, tardive…
(4.1) where A(t) is the arterial activity as a function of measurement time (t), τ is time, k u is the unidirectional influx rate, and V n is the initial…
Fig. 40.1 Magnetic resonance imaging. (a) A 5-year-old female patient with right frontal lobe epilepsy treated in our center. T1- and T2-weighted sequences showed widespread bilateral cortical atrophy that did…
1. Central feature (essential for a diagnosis of possible or probable DLB) Dementia defined as progressive cognitive decline of sufficient magnitude to interfere with normal social or occupational function. Prominent…
Fig. 18.1 T2-weighted MR images of the patient showing an infarct in the left temporal area (a: 1st stroke), with another infarct in the right frontal area (b: 2nd stroke),…
Fig. 23.1 Typical MR image of a BAVM 23.2.2 Natural History After the clinical presentation of a BAVM, the most important issue is the estimate of the natural disease course…
Fig. 20.1 Section of the cingulate cortex of an Alzheimer patient (F, 84 years) stained for amyloid plaques with the Gallyas modification of the Bielschowsky silver method. Upper panel shows…