The Default Network of the Brain
Fig. 8.1 (a) The default network of the human brain as it was originally identified in a meta-analysis of nine positron emission tomography (PET) studies (132 healthy young adults) from…
Perfusion SPECT: Its Role in the Diagnosis and Differential Diagnosis of Alzheimer’s Disease, with Particular Emphasis on Guidelines
Studies Diagnosis Sensitivity (%) Specificity (%) Accuracy (%) Jobst et al. (1992a) (n = 118) DSM-IIIR 51 97 66 NINCDS-ADRDA 93 61 77 Possible AD NINCDS-ADRDA 49 100 66 Probable AD NINCDS-ADRDA…
PET and SPECT in Hepatic and Uraemic Encephalopathy
Imaging procedure Author, year Patients Key finding Tc-99m-HMPAO-, Tc-99m-ECD-, I-123-IMP- or I-133-xenon- SPECT Blend et al. (2010) HE and carotid stenosis Regional hypoperfusion Catafau et al. (2000) Subclinical HE Regional…
PET Imaging in Multiple Sclerosis: Focus on the Translocator Protein
Fig. 35.1 Schematic representation of the rationale underlying the use of TSPO PET imaging to visualize the neuroinflammatory pathology in MS. The activation of microglia due to neuroinflammatory processes is…
PET and SPECT Studies of Ageing and Cardiovascular Risk Factors for Alzheimer’s Disease
Fig. 21.1 (a) Areas of reduced regional cerebral blood flow (rCBF) (as assessed with [99mTc]-HMPAO-SPECT) in patients with heart failure (HF) relative to healthy controls are highlighted in yellow, overlaid…
SPECT Imaging for Idiopatic M. Parkinson and Parkinsonian Syndromes: Guidelines and Comparison with PET and Recent Developments
123I-FP-CT SPECT 123I-IBZM SPECT Primary indications Primary indication Differentiating essential tremor from parkinsonian syndromes related to PD, MSA and PSP Differential diagnosis of parkinsonian syndromes Differentiation of dementia with LBD…
Modulation of Brain Functioning by Deep Brain Stimulation: Contributions from PET Functional Imaging
Drapier D, Drapier S, Sauleau P et al (2006) Does subthalamic nucleus stimulation induce apathy in Parkinson’s disease? J Neurol 253(8):1083–1091PubMed Dujardin K, Blairy S, Defebvre L et al (2004)…
Imaging Brain Metastases of Neuroendocrine Tumors
Fig. 44.1 68Ga-DOTATOC PET scan of a patient with extensively metastasized neuroendocrine lung tumor, who also had a small brain metastasis (red arrow) as well as an ossal lesion in…
The Value of 11C-Methionine PET in the Differential Diagnosis Between Brain Tumor Recurrence and Radionecrosis
Fig. 43.1 Examples of the ability of MET-PET to differentiate between tumor progression/recurrent tumor and radionecrosis. Left images, MRI; middle images, MET-PET; right images, fusion. (a) Tumor progression and (b)…
