Tumors of the Pineal Region Overview Primary tumors of the pineal region are comprised largely of four different histologic subtypes—pineocytoma, pineal parenchymal tumor of intermediate differentiation (PPTID), pineoblastoma, and papillary…
Germ Cell Tumors Overview Germ cell tumors (GCTs) are a heterogeneous group of central nervous system (CNS) tumors with morphologic, immunophenotypic, and genetic homologs of gonadal and other extra-CNS germ…
Mesenchymal Tumors Overview Mesenchymal tumors are thought to originate from precursor mesodermal cells that develop into bone, cartilage, or connective tissues, such as fibroblasts, smooth muscle cells, blood vessels, and…
Histiocytic Tumors Overview Histiocytic tumors are a rare heterogeneous group of tumor of the hematopoietic and lymphoid tissues and broadly classified into two categories: Langerhans cell histiocytosis and non-Langerhans histiocytosis….
Melanocytic Tumors Overview Primary melanocytic tumors of the central nervous system (CNS) are rare tumors, distinct and unrelated to systemic melanoma, that can be focal or diffuse and arise from…
CNS Lymphomas Overview CNS lymphomas are extranodal, non-Hodgkin’s lymphomas confined to the brain and spine comprised of malignant lymph tissues. Vast majority (˜90%) are diffuse large B-cell lymphomas arising inside…
Meningiomas Overview Meningiomas are the most common primary brain tumors in adults and comprise a group of mostly benign, slow-growing solid neoplasms that likely originated from meningothelial or arachnoid cells…
Imaging Modalities for Central Nervous System Tumors Overview In the current state of the rapidly developing molecular genetic era of brain tumor diagnosis and classification, the imaging and clinical management…
