Pediatric considerations for proton therapy
Introduction Approximately 10,500 cases of childhood cancer are diagnosed each year, which represent about 1% of all new cancers in the United States. Nearly 45% of these cancers will either…
Proton therapy for hematologic malignancies
Introduction As early as the 1970s, proton therapy was considered a promising treatment for hematologic malignancies, specifically for use in total nodal irradiation, the historic standard of care treatment for…
Lung cancer
Introduction Lung cancer is one of the most common malignancies, accounting for approximately 234,000 new cases and 160,000 deaths per year in the United States. Treatment for lung cancer depends…
Esophagus cancer
Introduction Esophageal cancer (EC) is the sixth leading cause of cancer death worldwide and is responsible for 400,000 new cases (4.9% of all cancers) cancer deaths annually. The incidence of…
Proton therapy and sarcomas
Introduction Sarcomas are a rare and heterogenous group of malignant tumors that arise from soft tissues or bone. They constitute less than 1% of all adult malignancies and approximately 12%…
Pediatric considerations for proton therapy
Introduction Approximately 10,500 cases of childhood cancer are diagnosed each year, which represent about 1% of all new cancers in the United States. Nearly 45% of these cancers will either…
Technological advancements and outlook in proton therapy
Introduction Intensity-modulated proton therapy (IMPT) using pencil beam scanning (PBS) technology has revolutionized the practice of particle therapy in recent years. , In PBS delivery, a particle pencil beam is…
Proton therapy for gynecologic malignancies
Introduction Each year more than 90,000 women are diagnosed with a gynecologic (ovarian, vulvar, vaginal, cervical, uterine, fallopian tube, or primary peritoneal) cancer in the United States. Radiotherapy is often…
Proton therapy for prostate cancer
Introduction The use of proton therapy for the treatment of cancer was first proposed by Robert Wilson in 1946. A beam of protons gives most of its dose at a…
Physics quality assurance
Introduction This chapter describes the physics quality assurance (QA) program for the proton pencil beam scanning (PBS) gantry of the Hitachi ProBeat machine (Hitachi America, Ltd., Tarrytown, NY) at the…
