History of Charged Particle Radiotherapy Herman D. Suit William Chu Ernest Rutherford, Nobel laureate in 1908 in Chemistry, demonstrated the existence of the proton in 1919.1,2 Robert Wilson, Harvard University,…
Imaging the Neovasculature A. J. Beer H. J. Wester M. Schwaiger Angiogenesis, the formation of new blood vessels, is a fundamental process involved in a variety of physiological as well…
Progress in Amyloid Imaging Brian J. Lopresti William E. Klunk Chester A. Mathis Alzheimer’s disease (AD) is the most prevalent form of dementia afflicting the elderly population and is characterized…
PET Imaging as a Biomarker Wolfgang A. Weber Caroline C. Sigman Gary J. Kelloff Biomarkers have been defined as “characteristics that are objectively measured and evaluated as indicators of normal…
The Kidneys Zsolt Szabo Jinsong Xia William B. Mathews Rationale The successful application of positron emission tomography (PET) in cancer is expected to translate to other diseases. Considerable progress can…
PET and Drug Development Jerry M. Collins Development of a drug is a process that depends heavily on knowledge of its distribution in the body and its effects on the…
Imaging Gene Expression Uwe Haberkorn After the identification of new genes, functional information is required to investigate the role of these genes in living organisms. This can be done by…
PET/CT Imaging of Infection and Inflammation Ora Israel Nuclear medicine plays an important role in the assessment of a multitude of infectious and inflammatory processes. Functional scintigraphic procedures are part…
Oxidative Metabolism and Cardiac Efficiency Heikki Ukkonen Rob S.B. Beanlands Oxidative metabolism of fuels provides the heart with the energy required for contraction and basal metabolism. Impaired myocardial energy transfer…
Myocardial Neurotransmitter Imaging Markus Schwaiger Ichiro Matsunari Frank M. Bengel The innervation of the heart represents an important aspect for the adaptation of cardiac performance to the hemodynamic requirements in…
