Treatment Planning
Treatment Planning CHAPTER 8.A PRINCIPLES OF SYSTEMS AND OPTIMIZATION Hanne M. Kooy Alexei Trofimov Martijn Engelsman Alfred R. Smith Robert Wilson in 1946, while directing the design of the second…
Pediatric Tumors
Pediatric Tumors Torunn Yock Thomas F. DeLaney Brittany Esty Nancy J. Tarbell RADIATION THERAPY FOR PEDIATRIC TUMORS Although the incidence of childhood cancer has stabilized over the last few years,…
Overview of Experience with Heavier Charged Particle Radiotherapy
Overview of Experience with Heavier Charged Particle Radiotherapy Hirohiko Tsujii Tadashi Kamada Juergen Debus In cancer therapy, the question is often raised whether improved local control could be associated with…
Clinical Issues in Proton Radiotherapy
Clinical Issues in Proton Radiotherapy Thomas F. DeLaney The unequivocal evidence that higher radiation doses to the tumor result in higher rates of local tumor control in animals1 and patients2…
Patient Positioning and Set-up Verification for Planning and Treatment
Patient Positioning and Set-up Verification for Planning and Treatment Martijn Engelsman Alejandro Mazal David A. Jaffray The last 10 years have seen a significant effort in the field of radiation…
Quality Assurance for Proton Therapy
Quality Assurance for Proton Therapy Richard L. Maughan Jonathan B. Farr INTRODUCTION The Role of Quality Assurance in Radiation Oncology The aim of quality assurance (QA) within a hospital environment…
Particle Accelerators
Particle Accelerators Jay Flanz INTRODUCTION TO THE PHYSICS OF PARTICLE ACCELERATORS Particle accelerators increase the kinetic energy of charged particles. For the purposes of particle therapy, this increase is equivalent…
Facility Design
Facility Design Edward T.M. Tsoi Jay Flanz A particle therapy facility contains a sophisticated combination of technical and medical equipment and houses personnel with a wide variety of skills, including…
Radiobiology of Charged Particles
Radiobiology of Charged Particles Leo Gerweck Harald Paganetti ENERGY DEPOSITION AND RELATIVE BIOLOGICAL EFFECTIVENESS The number of ionized biomolecules produced per unit dose of protons, heavier charged particles and x-rays…
History of Charged Particle Radiotherapy
History of Charged Particle Radiotherapy Herman D. Suit William Chu Ernest Rutherford, Nobel laureate in 1908 in Chemistry, demonstrated the existence of the proton in 1919.1,2 Robert Wilson, Harvard University,…
