(1) . 2. Tumor (cell) dimensions: Assume a “typical” tumor cell of spherical shape with r = 5 μ radius. The volume of this cell v = 4/3 × π × r3 = 4 × 125 μ3 = 5 × 10−10 cm3. (2) 3. Isotope ( 213…
Device References SPECT AXIS DST Xli Millenium VG Symbia (Staelens et al. 2003) (Assie et al. 2005; Autret et al. 2005) (Autret et al. 2005) (Carlier et al. 2006; Carlier…
Fig. 1 Schematic diagram of radiolabeling a peptide or protein via a bifunctional chelating agent (BCA) Table 1 Therapeutic radionuclides Radionuclide Type of emission Physical half-life Ionic radius (pm) Charge Emax (MeV)…
Fig. 1 a Otoscopic view of the myriongotomy tube of the left tympanic membrane before positioning of the applicator tube. b Otoscopic view of the ideal position of the applicator tube…
Fig. 1 Scheme illustrating the principle of pretargeting: a the biotinylated antibody binds to the antigen expressed at the surface of the tumor cell, b binding of avidin with high affinity…
Fig. 1 WBS (a) and chest CT (b) performed after the 1st administration of 3.7 GBq of 131I ; WBS (c) and chest CT (d) performed after the 4th administration of 3.7 GBq…
Fig. 1 Serial whole-body scans after intrathecal injection of 0.5 mCi of In-111 DTPA via an Ommaya reservoir (a), or via lumbar puncture (b). Patency of CSF is demonstrated in both cases…
Fig. 1 Intraperitoneal carcinomatosis with ascites 5 weeks after i.p. injection of MDA-MB435S cells expressing mutant E-cadherin into nude mice. a Section of an i.p. nodule (H&E staining) with tumour cells…
Peptide Receptor types/subtypes Tumor expression Somatostatin sst1, sst 2 , sst3, sst4, sst5 Neuroendocrine tumors (gastroenteropancreatic tumors), lymphoma, paraganglioma, carcinoids, breast, brain, renal, small cell lung cancer, medullary thyroid cancer…
Fig. 1 Whole-body 111In-octreotide scintigraphy in a patient with lung and bone metastases from papillary thyroid cancer (from Stokkel et al. (2004)—Fig. 1) Two studies concluded that octreotide scintigraphy has a lower…
