Abstract The head and neck have complex anatomy and there are multiple causes of physiologic FD avidity in the head and neck. Proper evaluation of benign and malignant lesions depends…

Abstract FDG-avid adrenal lesions may be malignant (metastases, lymphoma, adrenal cortical carcinoma) or benign (such as adenomas). Most benign adrenal neoplasms demonstrate background FDG avidity; however, a small percentage of…

Abstract FDG-avid splenic lesions may be malignant (lymphoma most commonly) or benign, such as infections and sarcoid. Benign causes of splenic FDG avidity are common and must be distinguished from…

Abstract FDG PET/CT is a hybrid functional and anatomical imaging method with substantial application in oncology. This chapter introduces FDG PET/CT and how the functional and anatomic components combine into…

Abstract The lung is an organ where integration of data from FDG PET, the CT, and the clinical history is particularly important. There are many FDG-avid lung lesions which will…

Abstract For oncologic FDG PET/CT scans, the patient is in the fasted state and the myocardium has variable utilization of glucose versus other sources of energy for metabolism. This results…

Abstract Muscles and nerves may demonstrate benign physiologic FDG avidity and must be distinguished from malignancy. This chapter describes common appearances of benign FDG avidity in muscles and nerves and…

Abstract FDG avidity in the thymus is often benign thymic rebound. The characteristic triangular shape of benign thymus will distinguish it from malignancy. Thymic malignancies are uncommon, but include thymic…

Abstract FDG avidity in the pleura may be malignant, such as metastases and mesothelioma, or benign, such as postpleurodesis inflammation. Corresponding CT findings, such as high attenuation from prior talc…

Abstract Optimal FDG PET/CT relies upon proper performance of the examination and reporting of the results. This chapter discusses proper patient preparation for FDG PET/CT, quantification of FDG uptake, and…