Accurate diagnosis of Aβ pathology Prognosis of conversion to AD Assessment of the spatial and temporal pattern of Aβ deposition and its relation to disease progression, cognitive decline and other…
Fig. 42.1 (a) Gadolinium enhanced T1-weighted MRI revealing recurrence of an anaplastic oligoastrocytoma. (b) 99mTc-Tetrofosmin brain SPECT revealing increased tracer uptake in the corresponding area Fig. 42.2 (a) T1-weighted MRI…
Fig. 8.1 (a) The default network of the human brain as it was originally identified in a meta-analysis of nine positron emission tomography (PET) studies (132 healthy young adults) from…
Studies Diagnosis Sensitivity (%) Specificity (%) Accuracy (%) Jobst et al. (1992a) (n = 118) DSM-IIIR 51 97 66 NINCDS-ADRDA 93 61 77 Possible AD NINCDS-ADRDA 49 100 66 Probable AD NINCDS-ADRDA…
Imaging procedure Author, year Patients Key finding Tc-99m-HMPAO-, Tc-99m-ECD-, I-123-IMP- or I-133-xenon- SPECT Blend et al. (2010) HE and carotid stenosis Regional hypoperfusion Catafau et al. (2000) Subclinical HE Regional…
Fig. 35.1 Schematic representation of the rationale underlying the use of TSPO PET imaging to visualize the neuroinflammatory pathology in MS. The activation of microglia due to neuroinflammatory processes is…
Fig. 21.1 (a) Areas of reduced regional cerebral blood flow (rCBF) (as assessed with [99mTc]-HMPAO-SPECT) in patients with heart failure (HF) relative to healthy controls are highlighted in yellow, overlaid…
123I-FP-CT SPECT 123I-IBZM SPECT Primary indications Primary indication Differentiating essential tremor from parkinsonian syndromes related to PD, MSA and PSP Differential diagnosis of parkinsonian syndromes Differentiation of dementia with LBD…
Drapier D, Drapier S, Sauleau P et al (2006) Does subthalamic nucleus stimulation induce apathy in Parkinson’s disease? J Neurol 253(8):1083–1091PubMed Dujardin K, Blairy S, Defebvre L et al (2004)…
