Paget’s Disease, Fibrous Dysplasia, Sarcoidosis, and Amyloidosis of Bone
Key Facts Paget’s Disease • The cause of Paget’s disease is not known. • Patients are frequently asymptomatic. • It is often an incidental finding on imaging studies. • It…
Oncogenic Osteomalacia
Key Facts • Osteomalacia resulting from the presence of a bone or soft tissue lesion or tumor is known as oncogenic osteomalacia or tumor-induced osteomalacia (TIO). • Adults are usually…
Crystal Diseases
Key Facts Gout • Clinically significant attacks may occur many years before radiographic changes are evident. • Radiographs classically show well-defined erosions with overhanging edges and sclerotic borders. • Soft…
Percutaneous Spine Interventions: Discography, Injection Procedures (Epidural Corticosteroids and Facet Joint and Sacroiliac Joint Injections), and Vertebral Augmentation (Vertebroplasty and Kyphoplasty)
Key Facts • Spine injection procedures can be helpful in localizing pain to a particular source (nociceptor) and in treating symptoms. • Careful image guidance is necessary to optimize results…
Seronegative Spondyloarthropathies and SAPHO Syndrome
Key Points • Seronegative spondyloarthropathies are interrelated chronic inflammatory rheumatic diseases that include ankylosing spondylitis (AS), reactive arthritis, psoriatic spondyloarthropathy, spondyloarthropathy associated with inflammatory bowel disease (IBD), and undifferentiated spondyloarthropathy….
Rickets and Osteomalacia
Key Facts • Rickets and osteomalacia result from inadequate or delayed mineralization of newly synthesized organic matrix (osteoid) in mature bone (osteomalacia) or growing bone (rickets). • The causes of…
Osteoarthritis
Key Points • Osteoarthritis involves all structures of the joint. • Osteoarthritis is the most common form of arthritis. • There is no direct correlation between radiographic findings and symptoms….
Hemochromatosis, Wilson’s Disease, Ochronosis, Fabry Disease, and Multicentric Reticulohistiocytosis
Key Facts Hemochromatosis • Most cases are due to a mutation that results in increased iron absorption from the gut. • Secondary hemochromatosis is due to iron overload from other…
Scleroderma and Related Disorders
Key Facts Musculoskeletal System • Radiographs can demonstrate the characteristic features of systemic sclerosis including calcinosis, loss of normal distal soft tissue and skin creases, and osteolysis that particularly involves…
Gaucher’s Disease
Key Facts • Gaucher’s disease is an autosomal recessive condition. • Deficiency of beta glucosidase leads to accumulation of glucosylceramide in lysosomes of monocyte/macrophage lineage. • Hepatosplenomegaly and replacement of…
