Tumors of the Sellar Region
Tumors of the Sellar Region Overview The genetic underpinnings of adamantinomatous and papillary craniopharyngiomas are very different, suggesting that they are each a distinct tumor entity although they share the…
Tumors of the Cranial and Paraspinal Nerves
Tumors of the Cranial and Paraspinal Nerves Overview Tumors of the cranial and paraspinal nerves are usually benign, slow-growing neoplasms composed of one or more elements of a nerve cell…
Tumors of the Pineal Region
Tumors of the Pineal Region Overview Primary tumors of the pineal region are comprised largely of four different histologic subtypes—pineocytoma, pineal parenchymal tumor of intermediate differentiation (PPTID), pineoblastoma, and papillary…
Germ Cell Tumors
Germ Cell Tumors Overview Germ cell tumors (GCTs) are a heterogeneous group of central nervous system (CNS) tumors with morphologic, immunophenotypic, and genetic homologs of gonadal and other extra-CNS germ…
Mesenchymal Tumors
Mesenchymal Tumors Overview Mesenchymal tumors are thought to originate from precursor mesodermal cells that develop into bone, cartilage, or connective tissues, such as fibroblasts, smooth muscle cells, blood vessels, and…
Histiocytic Tumors
Histiocytic Tumors Overview Histiocytic tumors are a rare heterogeneous group of tumor of the hematopoietic and lymphoid tissues and broadly classified into two categories: Langerhans cell histiocytosis and non-Langerhans histiocytosis….
Melanocytic Tumors
Melanocytic Tumors Overview Primary melanocytic tumors of the central nervous system (CNS) are rare tumors, distinct and unrelated to systemic melanoma, that can be focal or diffuse and arise from…
CNS Lymphomas
CNS Lymphomas Overview CNS lymphomas are extranodal, non-Hodgkin’s lymphomas confined to the brain and spine comprised of malignant lymph tissues. Vast majority (˜90%) are diffuse large B-cell lymphomas arising inside…
Meningiomas
Meningiomas Overview Meningiomas are the most common primary brain tumors in adults and comprise a group of mostly benign, slow-growing solid neoplasms that likely originated from meningothelial or arachnoid cells…
Imaging Modalities for Central Nervous System Tumors
Imaging Modalities for Central Nervous System Tumors Overview In the current state of the rapidly developing molecular genetic era of brain tumor diagnosis and classification, the imaging and clinical management…
