Author Tumor model Endpoint Results Additional observations Blackwood and Cooper [28] Myosarcoma and carcinosarcoma in rats Suppression of second tumors and resistance to rechallenge Significant impact of cryosurgery on regression…
Fig. 4.1 A schematic diagram of the physical principle of HIFU for noninvasive ablation. a HIFU transducer, focusing ultrasound energy into a small volume while ultrasound beams transmit through the…
Drug class Drug Pathway Reference Platinum compounds Cisplatin Extrinsic [15, 19] Oxaliplatina Intrinsic [20–22] Antimetabolites 5-fluorouracil Extrinsic [23] Gemcitabinea Intrinsic [24, 25] Methotrexate Extrinsic [26] Anthracyclines Doxorubicina Both [15, 17,…
3. Mellman I, Coukos G, Dranoff G (2011) Cancer immunotherapy comes of age. Nature 480:480–489PubMed 4. Klein O, Schmidt C, Knights A, Davis ID, Chen W, Cebon J (2011) Melanoma…
Fig. 7.1 Events and effector processes involved in host response to PDT of tumors 7.3.1 Onset and Advancement of Inflammatory Response The early stage of inflammation in PDT-treated tumor tissue…
Fig. 2.1 Temperature ranges used for hyperthermia The properties of the extracellular microenvironments of tumors are important in the outcome of hyperthermia treatments as will be discussed later. The unusual…
[15]. At doses around 2 Gy the linear alpha component is responsible for most cell kill whereas at higher doses the beta component gains in importance. If doses are fractionated, the…
Fig. 3.1 Induction of anti-tumor immunity by RFA combined with immunotherapy 3.5.2.1 Stimulation of Antigen Presentation The instantaneous release and availability of tumor antigens for antigen-presenting cells founded interest in…
