General Central Nervous System
General Central Nervous System Updated by Jingya Wang BACKGROUND What is the estimated annual incidence of primary CNS tumors in the U.S.? ~50,000–55,000 cases/yr of CNS tumors (per the National…
General Central Nervous System Updated by Jingya Wang BACKGROUND What is the estimated annual incidence of primary CNS tumors in the U.S.? ~50,000–55,000 cases/yr of CNS tumors (per the National…
Intracranial Germ Cell and Pineal Tumors Updated by Nikhil G. Thaker BACKGROUND What are the 2 broad categories of germ cell tumors? Gonadal and extragonadal Pineal tumors represent what %…
Craniopharyngioma Updated by Andrew J. Bishop BACKGROUND What is the origin of craniopharyngioma? Epithelial tumor derived from Rathke’s pouch, the embryonic precursor to the anterior pituitary In what region of…
Neuroblastoma Updated by Jingya Wang Background What are the 3 types of neuroblastic tumors? 3 types of neuroblastic tumors: 1. Neuroblastoma (NB) 2. Ganglioneuroblastoma 3. Ganglioneuroma These tumors differ in…
Medulloblastoma Updated by Nikhil G. Thaker BACKGROUND Estimate the annual incidence of medulloblastoma (MB) in the U.S. What is its frequency relative to other CNS tumors in children? ~500 cases/yr…
Retinoblastoma Updated by Vinita Takiar BACKGROUND What is the incidence and median age for presentation of retinoblastoma (RB)? 250–300 cases/yr of RB; 95% <5 yo (1 yo for familial, 2…
Ependymoma Steven H. Lin, Ori Shokek, and Updated by Mark Edson BACKGROUND In children and adults, what % of brain tumors are ependymomas? Children: 5% (3rd most common childhood CNS…
Langerhans Cell Histiocytosis Updated by Mark Edson BACKGROUND What is the estimated annual incidence of Langerhans cell histiocytosis (LCH) in the U.S.? ~1,200 cases/yr of LCH in the U.S. It…
Rhabdomyosarcoma Updated by Vinita Takiar BACKGROUND What are the 3 most commonly tested rhabdomyosarcoma (RMS) cases on the radiation oncology oral boards? Bladder (trigone), parameningeal (PM), and orbit What are…
Ewing Sarcoma Updated by Randa Tao WORKUP/STAGING What is the annual incidence of Ewing sarcoma (EWS) in the U.S.? How common is it relative to other bone tumors? 200 cases/yr…