Diffusion-weighted imaging has been used extensively in clinical practice for the early diagnosis of central nervous system conditions that restrict the diffusion of water molecules because it provides information about…
Diffusion weighting (DW) represents a magnetic resonance imaging contrast distinct from T1 and T2 in terms of imaging physics and its relationship to underlying physiology and pathophysiology. DW imaging has…
The role of magnetic resonance imaging in evaluating patients with inflammatory arthritides has evolved with the recent introduction of drugs capable of modifying disease activity and natural history. In conditions…
MR imaging has increasingly been used to image joints since its inception. Historically, there has been more emphasis on the evaluation of internal derangement rather than cartilaginous disease. This article…
Cartilage abnormalities in the knee and ankle are a common source of pain and are often difficult to diagnose clinically or radiographically. MR imaging is a valuable tool for diagnosing…
MR imaging is one of the most commonly used imaging techniques to evaluate patients with hip pain. Intra-articular abnormalities of the hip joint are better assessed with recent advances in…
Semiquantitative assessment of the knee by expert magnetic resonance imaging readers is a powerful research tool for understanding the natural history of osteoarthritis (OA). Several reliable semiquantitative scoring systems have…
The newer magnetic resonance (MR) imaging methods can give insights into the initiation, progression, and eventual treatment of osteoarthritis. Sodium imaging is specific for changes in proteoglycan (PG) content without…
At each joint, the extracellular matrix of cartilage is arranged in a complex and characteristic organization that is specific for that joint. This structure exerts a strong influence on the…
An underlying hypothesis for rapid cartilage loss in patients with osteoarthritis (OA) is that perturbation from normal joint mechanics produces locally high biomechanical strains that exceed the material properties of…
