Imaging Genomics of Glioblastoma

Mar 13, 2017 by in NEUROLOGICAL IMAGING Comments Off on Imaging Genomics of Glioblastoma

Glioblastoma (GBM) is the most common and most aggressive primary malignant tumor of the central nervous system. Recently, researchers concluded that the “one-size-fits-all” approach for treatment of GBM is no…

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Genomics of Brain Tumor Imaging

Mar 13, 2017 by in NEUROLOGICAL IMAGING Comments Off on Genomics of Brain Tumor Imaging

Imaging genomics combines imaging-defined phenotypes with molecular determinants of disease. Recent studies have examined the relationship between MRI-derived feature sets and gene expression in gliomas, including glioblastoma (GBM). Several groups…

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Molecular Genetics of Glioblastomas

Mar 13, 2017 by in NEUROLOGICAL IMAGING Comments Off on Molecular Genetics of Glioblastomas

Despite comprehensive therapy, which includes surgery, radiotherapy, and chemotherapy, the prognosis of glioblastoma multiforme is very poor. Diagnosed individuals present an average of 12 to 18 months of life. This article…

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Understanding Genetics in Neuroimaging

Mar 13, 2017 by in NEUROLOGICAL IMAGING Comments Off on Understanding Genetics in Neuroimaging

Gene expression is a process of DNA sequence reading into protein synthesis. In cases of problems in DNA repair/apoptosis mechanisms, cells accumulate genomic abnormalities and pass them through generations of…

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