to fit A 0 and t 1/2 for easy calculation of the cumulated activity as Here, t 1/2 is the total half-life of the nuclide. A simple time-activity model is…
Fig. 1 (2-[18F]fluoroethyl)-l-tyrosine Despite all efforts, the success of utilizing radiolabeled amino acids to measure protein synthesis in vivo is still limited or unsatisfactory. The difficulties in utilizing radiolabeled amino acids for…
Fig. 1 Structure of folic acid Whilst FA and its derivatives show excellent affinities to FR in the nanomolar range, solely pteroic acid shows a significant drop in affinity (Kamen and…
Fig. 1 Origin of registered neuroendocrine tumors Patients were heavily pretreated. In 218 patients, number and kind of previous therapies were documented and included in the registry. Of these 218 patients,…
Fig. 1 Schematic representation of the proposed mechanism underlying binding of nitroimidazole tracers in hypoxic cell. Reprinted with permission from Stroke 2008, 39, 1629–1637. Copyright (2008) American Stroke Association Fig. 2 Proposed…
Site of SSTR-positive target lesions Maximum SUV before PRRNT Third Second First Liver S8 apical 12.6 13.2 14.0 S8 apicomedial/central 11.0 14.0 12.2 S2 medial 13.7 15.2 12.9 S5/S8/S7 with…
Fig. 1 Receptor autoradiography showing 177Lu-DOTA-BASS antagonist versus 177Lu-DOTATATE agonist binding in renal cancer (upper row), breast cancer (middle row), and non-Hodgkin lymphoma (lower row). a Total binding with the respective…
DOTATATE DOTATOC Age 60.2 ± 9.1 years 45.3−75.2 years Activity per cycle (GBq) 6.5 ± 1.1 7.3 ± 0.7 5.0−9.5 5.5−8.5 Table 2 Risk factors present in the patient group Risk factor No. of patients Hypertension 9 Diabetes…
Fig. 1 Frequency distribution of mean absorbed dose to the spleen in the 53 patients in the study group Fig. 2 177Lu posttherapy whole-body scans 20 h p.i. along with corresponding time-activity curves…
Fig. 1 HPLC profiles of DOTA-mAbs conjugations. (Right) reaction mixture. (Left) purified conjugate Fig. 2 Flow cytometric analysis. a Unmodified nimotuzumab, b (DOTA-Bz-SCN)4-5-h-R3, c (DOTA-Bz-SCN)8-9-h-R3, d (DOTA-Bz-SCN)14-15-h-R3 Several groups have reported radiolabeling…
