Bisphosphonates for Bone Pain Palliation
Tumour Mean frequency (%) Range (%) Breast 73 47–85 Prostate 68 33–85 Thyroid 42 28–85 Kidney 35 33–40 Lung 36 30–55 Oesophagus 6 5–7 Gastrointestinal 5 3–11 Rectum 11 8–13…
Between β-Emitting Isotopes and α-Emitters Regarding Their Effects on Cancer Cells
(1) . 2. Tumor (cell) dimensions: Assume a “typical” tumor cell of spherical shape with r = 5 μ radius. The volume of this cell v = 4/3 × π × r3 = 4 × 125 μ3 = 5 × 10−10 cm3. (2) 3. Isotope ( 213…
Carlo Methods in Nuclear Medicine
Device References SPECT AXIS DST Xli Millenium VG Symbia (Staelens et al. 2003) (Assie et al. 2005; Autret et al. 2005) (Autret et al. 2005) (Carlier et al. 2006; Carlier…
Radionuclides for Nuclear Medicine Therapy
Fig. 1 Schematic diagram of radiolabeling a peptide or protein via a bifunctional chelating agent (BCA) Table 1 Therapeutic radionuclides Radionuclide Type of emission Physical half-life Ionic radius (pm) Charge Emax (MeV)…
of Brain Tumors
Fig. 1 Scheme illustrating the principle of pretargeting: a the biotinylated antibody binds to the antigen expressed at the surface of the tumor cell, b binding of avidin with high affinity…
as a Treatment Option in Chronic Otitis Media and Paranasal Mucositis
Fig. 1 a Otoscopic view of the myriongotomy tube of the left tympanic membrane before positioning of the applicator tube. b Otoscopic view of the ideal position of the applicator tube…
of Thyroid Cancer Patients and Treatment of Distant Metastases
Fig. 1 WBS (a) and chest CT (b) performed after the 1st administration of 3.7 GBq of 131I ; WBS (c) and chest CT (d) performed after the 4th administration of 3.7 GBq…
Radionuclide Therapy of Primary and Metastatic Cancers
Fig. 1 Serial whole-body scans after intrathecal injection of 0.5 mCi of In-111 DTPA via an Ommaya reservoir (a), or via lumbar puncture (b). Patency of CSF is demonstrated in both cases…
for Nuclear Medicine Therapy: Chemical Properties and Production
Peptide Receptor types/subtypes Tumor expression Somatostatin sst1, sst 2 , sst3, sst4, sst5 Neuroendocrine tumors (gastroenteropancreatic tumors), lymphoma, paraganglioma, carcinoids, breast, brain, renal, small cell lung cancer, medullary thyroid cancer…
Alpha Particle Therapy of Peritoneal Carcinomas
Fig. 1 Intraperitoneal carcinomatosis with ascites 5 weeks after i.p. injection of MDA-MB435S cells expressing mutant E-cadherin into nude mice. a Section of an i.p. nodule (H&E staining) with tumour cells…
