Myeloablative radioimmunotherapy Aim of therapy Reduction of tumor cell number Conditioning prior to SCT by: Reduction of tumor cell number Myeloablation Antibody specification Tumor cell affinity Bone marrow affinity (Tumor…
Fig. 1 Schematic diagram of prostate carcinoma cell depicting transmembrane prostate specific membrane antigen (PSMA). The extracellular portion binds antibody J591 which has been used labeled with Lutetium-177 and other radionuclides…
Antithyroid drug Surgery Radioiodine Time to initial improvement 2–4 weeks Needs antithyroid drug pretreatment (toxic goiters) Needs antithyroid drug pretreatment; 4–8 weeks after RIT Recurrence 90–100 % (toxic goiters) 1–4 %…
Fig. 1 Example of a delineated volume of interest (VOI). The 3D boundary is approximated by a series of 2D contours (orange). The volume (tumour) is shown in the anatomical context…
Fig. 1 Reduction of neointima formation due to irradiation: Cross-sections of rabbit carotid arteries at 4 weeks after denudation trauma (magnification × 10). Control artery (left) demonstrates intense neoinitimal proliferation. Following endovascular irradiation from…
Fig. 1 General study conduct of PRRT at the department of nuclear medicine, medical university of innsbruck. Within the music project different types of music were applied via MP3 players during…
Tumour Mean frequency (%) Range (%) Breast 73 47–85 Prostate 68 33–85 Thyroid 42 28–85 Kidney 35 33–40 Lung 36 30–55 Oesophagus 6 5–7 Gastrointestinal 5 3–11 Rectum 11 8–13…
(1) . 2. Tumor (cell) dimensions: Assume a “typical” tumor cell of spherical shape with r = 5 μ radius. The volume of this cell v = 4/3 × π × r3 = 4 × 125 μ3 = 5 × 10−10 cm3. (2) 3. Isotope ( 213…
Device References SPECT AXIS DST Xli Millenium VG Symbia (Staelens et al. 2003) (Assie et al. 2005; Autret et al. 2005) (Autret et al. 2005) (Carlier et al. 2006; Carlier…
Fig. 1 Schematic diagram of radiolabeling a peptide or protein via a bifunctional chelating agent (BCA) Table 1 Therapeutic radionuclides Radionuclide Type of emission Physical half-life Ionic radius (pm) Charge Emax (MeV)…
