Cerebral Perfusion MRI in Mice
Mean CBF 121 ± 14 Telencephalon Regional CBF Hippocampus CA1 114 ± 15 Cerebellum Hippocampus CA2 98 ± 17 Cerebellar cortex 145 ± 17 Hippocampus CA3…
Mean CBF 121 ± 14 Telencephalon Regional CBF Hippocampus CA1 114 ± 15 Cerebellum Hippocampus CA2 98 ± 17 Cerebellar cortex 145 ± 17 Hippocampus CA3…
The normalization takes into account that small signal differences can easily be masked when the overall signal intensity is high. It should be kept in mind that the ability to…
([1]) where N m is the number of spins in the state m, N 0 is the total number of spins, E m is the energy of the state m,…
([1]) where γ is the gyromagnetic ratio; ћ is Planck’s constant divided by 2π; P is the nuclear spin polarization. Therefore, it is clear that a higher spin concentration and…
([1]) where B 0 is the strength of the external magnetic field (measured in Tesla), ω 0 and ν 0 are the angular velocity and frequency of the precession, respectively,…
Mouse (rapid bolus i.v.) Rat (rapid bolus i.v.) Dog (rapid bolus i.v.) Max vol. (mL/kg) Max rate (mL/s) Max vol. (mL/kg) Max rate (mL/s) Max vol. (mL/kg) Max. rate…
, does not contain any position-dependent terms. It is thus necessary to introduce some spatially varying factor that allows distinguishing between spins at different positions in space. This is achieved…
Fig. 1. Cartoon depicting the mechanism of CEST contrast for lL-arginine dissolved in water. (a) Saturation pulses are placed either on resonance with the exchangeable guanidyl protons or off resonance…
, that can be tuned by changing the strength GT of the magnetic field gradient pulses used in the iMQC experiments. This distance is usually chosen to be smaller than…
Fig. 1. Schematic representation of the vertebral segments and sagittal, coronal, and axial MR images of the spinal cord at the cervical, thoracic, and lumbar levels. The arrows (sagittal and…