MRI of CEST-Based Reporter Gene
Fig. 1. Flowchart of the CEST imaging protocol for in vivo reporter gene imaging. 2 Materials 2.1 General Requirements 1. A high-field (4.7 T and above), small animal narrow bore…
Manganese-Enhanced Magnetic Resonance Imaging
Transport system References Divalent metal transporter (DMT1, also known as NRAMP-2 or DCT-1) (33, 197–199) Transferrin–transferrin receptor system (21, 28, 80, 200) Voltage-gated calcium channels (44) Store-operated calcium channels (201)…
Scanner Components
Fig. 1. Conceptual setup of a superconducting magnet with a vertical bore. The superconducting coils that cylindrically surround the bore are placed in a chamber filled with liquid helium. To…
High Field Diffusion Tensor Imaging in Small Animals and Excised Tissue
([1]) The mean squared displacement can then be calculated from the second moment of this distribution: ([2]) This is the well-known Einstein equation of diffusion and this model is used…
Analysis of Freshly Fixed and Museum Invertebrate Specimens Using High-Resolution, High-Throughput MRI
Higher taxon Species References Scanning condition Demospongiae Haplosclerida Lubomirskia baicalensis (5)a Ex vivo Crustacea Decapoda Callinectes sapidus (6)a In vivo Cancer pagurus (7) In vivo Maja squinado (7) In vivo …
Target-Specific Paramagnetic and Superparamagnetic Micelles for Molecular MR Imaging
Fig. 1. T 1-weighted MR images and confocal laser scanning microscopy (CLSM) images taken from the carotid artery of mice injected with collagen-targeted paramagnetic micelles. These micelles were equipped with…
Mouse Phenotyping with MRI
Fig. 1. The mouse sled used to position the mouse and provide physiological contacts (36). (a) The sled indicating the Velcro attachment to secure the mouse’s head. (b) A close-up…
BOLD MRI Applied to a Murine Model of Peripheral Artery Disease
Fig. 1. Materials for reactive hyperemia surgery. (a) Occlusion tube. (b) Bisected end of occlusion tube through which the 6-lb test fishing line is threaded and which is placed into…
MR for the Investigation of Murine Vasculature
Fig. 1. MIP view of the renal vessels superimposed with a surface-rendered view of the kidneys for anatomical orientation. The angiogram was reconstructed from a 2D multislice dataset which was…
Cancer Models—Multiparametric Applications of Clinical MRI in Rodent Hepatic Tumor Model
Fig. 1. MR imaging setup for rodents. A rat was placed supinely into a homemade plastic holder covered with a homemade mask connecting to an inhalation anesthesia system via a…
