The use of MR imaging–derived methods to provide sensitive and reproducible assessments of brain volume (eg, to estimate atrophy) has increased the interest in this measure as a reliable indicator…
Computerized image analysis is becoming more routine in multiple sclerosis research. This article reviews the common types of task that are performed when producing quantitative measures of disease status, progression,…
Magnetic resonance (MR) imaging has become the dominant clinical imaging modality with widespread, primarily noninvasive, applicability throughout the body and across many disease processes. The flexibility of MR imaging enables…
Conventional MR imaging refers to techniques that are readily available and widely used in the diagnosis and monitoring of individuals with multiple sclerosis (MS). MR imaging is helpful in establishing…
Multiple sclerosis is widely recognized as the most commonly identified cause of progressive neurologic disability in young adults throughout the developed world. The disorder is clinically suspected when patients experience…
Multiple sclerosis (MS) pathology is originally defined by the presence of focal white matter lesions, characterized by inflammation, primary demyelination, and reactive glial scaring. More recently, however, it became clear…
This article explores the role of high-field (HF) MR imaging in medicine. It analyzes advantages of HF MR imaging in application to human subjects and how best they can be…
Conventional MR imaging is, at present, the most important paraclinical modality for assessing the risk of MS in patients with acute demyelinating ON and for monitoring the progression of disease….
This article provides an overview of relaxation times and their application to normal brain and brain and cord affected by multiple sclerosis. The goal is to provide readers with an…
MR imaging has had a major impact on understanding the dynamic neuropathologic findings of multiple sclerosis (MS), early diagnosis of the disease, and clinical trial conduct. The next 10 years…
