Clinical Issues in Proton Radiotherapy
Clinical Issues in Proton Radiotherapy Thomas F. DeLaney The unequivocal evidence that higher radiation doses to the tumor result in higher rates of local tumor control in animals1 and patients2…
GENERAL RADIOLOGY
Patient Positioning and Set-up Verification for Planning and Treatment
Patient Positioning and Set-up Verification for Planning and Treatment Martijn Engelsman Alejandro Mazal David A. Jaffray The last 10 years have seen a significant effort in the field of radiation…
Quality Assurance for Proton Therapy
Quality Assurance for Proton Therapy Richard L. Maughan Jonathan B. Farr INTRODUCTION The Role of Quality Assurance in Radiation Oncology The aim of quality assurance (QA) within a hospital environment…
Particle Accelerators
Particle Accelerators Jay Flanz INTRODUCTION TO THE PHYSICS OF PARTICLE ACCELERATORS Particle accelerators increase the kinetic energy of charged particles. For the purposes of particle therapy, this increase is equivalent…
Facility Design
Facility Design Edward T.M. Tsoi Jay Flanz A particle therapy facility contains a sophisticated combination of technical and medical equipment and houses personnel with a wide variety of skills, including…
Radiobiology of Charged Particles
Radiobiology of Charged Particles Leo Gerweck Harald Paganetti ENERGY DEPOSITION AND RELATIVE BIOLOGICAL EFFECTIVENESS The number of ionized biomolecules produced per unit dose of protons, heavier charged particles and x-rays…
History of Charged Particle Radiotherapy
History of Charged Particle Radiotherapy Herman D. Suit William Chu Ernest Rutherford, Nobel laureate in 1908 in Chemistry, demonstrated the existence of the proton in 1919.1,2 Robert Wilson, Harvard University,…
Renal Mass Biopsy
Fig. 17.1 A 48-year-old man with melanoma. An axial CT image of the abdomen reveals a hypervascular mass in the right kidney. A biopsy revealed renal cell carcinoma Fig. 17.2…
Biopsy of Head and Neck Lesions
Fig. 9.1 (a–h). Schematic drawings showing axial cross-sectional anatomy at various levels in the head and neck region. In each figure, the anatomic structures are shown on the left and…
Percutaneous Transthoracic Lung Biopsy
Fig. 11.1 Solitary pulmonary nodule: two different patients (a–b and c–d) undergoing TCNB for an indeterminate pulmonary nodule. (a) Pre-biopsy image demonstrates a 20 mm lobulated nodule within the left…
