Unusual Cerebral Emboli
Key points • A multiplicity of acute small infarcts in different vascular territories is a common manifestation of cerebral embolism. • Diffuse white matter blooming foci on T2* MR imaging…
Three-Dimensional Ultrasound of Carotid Plaque
Measurement of plaque burden is different from measurement of carotid intima-media thickness (IMT). Carotid total plaque area is a stronger predictor of cardiovascular risk than IMT, and in contrast to…
Analysis of Multicontrast Carotid Plaque MR Imaging
Plaque imaging by MR imaging provides a wealth of information on the characteristics of individual plaque that may reveal vulnerability to rupture, likelihood of progression, or optimal treatment strategy. T1-weighted…
Low-Grade Carotid Stenosis
Key points • Luminal imaging techniques do not adequately evaluate extracranial carotid atherosclerotic plaque burden and characteristics in patients with low-grade carotid stenosis. • Although multiple randomized controlled trials have…
Plaque Imaging to Decide on Optimal Treatment
Many of the current guidelines for the management of carotid atherosclerosis are based on clinical trial findings published more than 2 decades ago. The lack of plaque information in clinical…
Clinical Perspective of Carotid Plaque Imaging
At present, patients with carotid disease are selected for invasive recanalization therapies mainly based on the degree of luminal narrowing and the presence or absence of recent ischemic symptoms. A…
Detection of Vulnerable Plaque in Patients with Cryptogenic Stroke
In up to 40% of ischemic stroke cases the etiology remains unknown. A substantial proportion of these patients has non- or only mildly stenosing carotid artery plaques not fulfilling common…
Plaque Assessment in the Management of Patients with Asymptomatic Carotid Stenosis
The continued occurrence of stroke despite advances in medical therapy for asymptomatic carotid stenosis (ACS) strongly indicates that individual response to medical therapy may vary widely. This article reviews the…
The Use of Contrast-enhanced Ultrasonography for Imaging of Carotid Atherosclerotic Plaques
Contrast-enhanced ultrasonography (CEUS) is a rapidly evolving modality for imaging carotid artery disease and systemic atherosclerosis. CEUS coupled with diagnostic ultrasonography predicts the degree of carotid artery stenosis and is…
Utility of Combining PET and MR Imaging of Carotid Plaque
By harnessing the versatility and soft tissue imaging capabilities of MR imaging alongside the unmatched sensitivity and biomolecular flexibility of PET, the potential to provide detailed multiparametric plaque characterization in…
