Medicine Dose Assessment

Sep 1, 2016 by in NUCLEAR MEDICINE Comments Off on Medicine Dose Assessment

(1) where = absorbed dose rate to a target region of interest (Gy/sec or rad/hr) A S  = activity (MBq or μCi) in source region S y i  = number of radiations…

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Lymphoma: Radioimmunotherapy Using Iodine-131 Labeled Murine Anti-CD20 Antibodies (131I-Tositumomab and Tositumomab, “Bexxar”)

Sep 1, 2016 by in NUCLEAR MEDICINE Comments Off on Lymphoma: Radioimmunotherapy Using Iodine-131 Labeled Murine Anti-CD20 Antibodies (131I-Tositumomab and Tositumomab, “Bexxar”)

Fig. 1 2D representation of the CD20 antigen (previously known as “B1”). Note that antibodies used in RIT bind to the extracellular domain. This figure was published in American Journal…

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Generator-Based Radiopharmaceuticals for Therapy

Sep 1, 2016 by in NUCLEAR MEDICINE Comments Off on Generator-Based Radiopharmaceuticals for Therapy

Fig. 1 Publications describing rhenium-188 radiopharmaceutical development and clinical trials (data from MedLine) From a clinical perspective, radionuclide therapy has a high impact in the treatment of benign diseases, such as…

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Concepts and Procedures

Sep 1, 2016 by in NUCLEAR MEDICINE Comments Off on Concepts and Procedures

   Global N = 206  Group under analysis All grades Grade 4 Radiation pneumonitis 206 treatments 1 (0.4 %) 0 GI ulcers 215 procedures 3 (1.4 %) 0 REILD (global) 206 treatments 24 (11 %)…

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Approaches: Combined Local and Multimodal Strategies in the Treatment of Complex Neuroendocrine Liver Metastases

Sep 1, 2016 by in NUCLEAR MEDICINE Comments Off on Approaches: Combined Local and Multimodal Strategies in the Treatment of Complex Neuroendocrine Liver Metastases

Type of disease Strategy Goal Single spots “rule of five” <5 cm diameter; <5 spots RFTA, (LITT), MW Complete destruction A0-ablation/curation Small hypervascularized lesion TAE with embozene; alternative: DC-Beads Complete destruction/curation Big…

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