The Imaging
and Rakhi Kaila2 (1) School of Physics, University of New South Wales, Sydney, NSW, Australia (2) School of Medicine, University of New South Wales, Sydney, NSW, Australia Abstract In the…
Conclusion and Future Horizons
and Rakhi Kaila2 (1) School of Physics, University of New South Wales, Sydney, NSW, Australia (2) School of Medicine, University of New South Wales, Sydney, NSW, Australia Abstract The resonance…
The Density Matrix Concept
and Rakhi Kaila2 (1) School of Physics, University of New South Wales, Sydney, NSW, Australia (2) School of Medicine, University of New South Wales, Sydney, NSW, Australia Abstract One naturally…
Summary and Conclusion
and Rakhi Kaila2 (1) School of Physics, University of New South Wales, Sydney, NSW, Australia (2) School of Medicine, University of New South Wales, Sydney, NSW, Australia Abstract The quantum…
Body Composition
BMI is widely used in clinical trials because it is effectively free and proportional to whole-body percent fat by other methods. Flegal and colleagues [2] found that BMI, waste circumference,…
Cardiac Imaging in Clinical Trials
Imaging modality Radiation dose Key measurements Common applications Echocardiography (2D, 3D, exercise stress, dobutamine stress, transesophageal) None Wall thickness, cardiac chamber size in systole or diastole, valvular anatomy and function,…
Optical Coherence Tomography as a Biomarker in Clinical Trials for Ophthalmology and Neurology
Fig. 13.1 One of the many illustrations of the human retina done by SR Cajal around 1880 that earned him the Nobel Prize in Medicine. While some details are incorrect,…
Neuroimaging in Clinical Trials
Criteria Measurement Score Heterogeneity (HET) None 0 Mild 1 Moderate 2 Marked 3 Cyst formation/necrosis (CN) None 0 Equivocal 1 Yes 2 Hemorrhage (HEM) None 0 Equivocal 1 Yes 2…
Contrast Agents in Radiology
Fig. 15.1 Number of performed or ongoing oncological and non-oncological registered clinical trials from 01/2007 to 06/2010 using contrast media, (a) to investigate the CM itself or (b) to diagnose/monitor…
The Metrics and New Imaging Marker Qualification in Medical Imaging Modalities
Predicted outcome Actual outcome Positive Negative Positive True-positive False-negative Negative False-negative True-negative With this concept, we can then calculate the sensitivity and specificity of the technique. The sensitivity is the…
